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Background: Chronic wounds can pose a significant challenge for patients and healthcare professionals including the morbidity and associated costs. It is therefore essential to understand the specific challenges faced by patients to make wound care services more effective and convenient for the patient population.
Aim: Using the PEO model, this systematic review aims to explore the specific challenges patients with chronic wounds encounter when attending medical appointments related to wound care.
Method: A systematic search of publications using MEDLINE, Ovid EMBASE, CINAHL databases was conducted in April 2024, and relevant articles were reviewed. Data extraction and a narrative synthesis approach was undertaken. The evidence-based librarianship (EBL) checklist assessed the methodological quality of the studies included. The primary outcome was to identify the specific challenges faced by patients with chronic wounds who attend medical appointments related to wound care. The secondary outcome was to determine wound healing progression, quality of life, complications of wound care, and adverse effects of wound care.
Results: Six studies between the years 2014 and 2024 described the specific challenges faced by patients with chronic wounds in a hospital or clinic setting. All six studies mentioned the pain and unwanted physical inactivity collectively affected the daily life of the patients and their capability of attending appointments. Increased cost of attending wound care appointments and travelling were elucidated by four studies. Increased waiting time during the appointments were also described by four studies. Additionally, two studies mentioned the difficulties of accessing public transport and heavy reliance on private transport because of the physical inability associated with the wound.
Conclusion: This systematic review identified several challenges faced by patients with chronic wounds when attending medical appointments. Key issues include increased waiting times, and the excessive cost of appointments. Pain, discomfort, and physical limitations further complicated attendance, particularly for distant clinics, leading to reliance on expensive private transport. Additionally, three studies reported decreased quality of life. These findings highlight the need for more effective and convenient wound care services for patients.
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http://dx.doi.org/10.1016/j.jtv.2025.100865 | DOI Listing |
Angiogenesis
September 2025
Pathophysiology and Regenerative Medicine Group, Hospital Nacional de Parapléjicos, Servicio de Salud de Castilla la Mancha (SESCAM), 45071, Toledo, Spain.
Limited vascularization and ischemia are major contributors to the chronicity of wounds, such as ulcers and traumatic injuries, which impose significant medical, social, and economic burdens. These challenges are particularly pronounced in patients with spinal cord injury (SCI), a disabling condition associated with vascular dysfunction, infections, and impaired peripheral circulation, complicating the treatment of pressure injuries (PIs) and the success of reconstructive procedures like grafts and flaps. Regenerative medicine aims to address these issues by identifying effective cellular therapies to restore vascular beds.
View Article and Find Full Text PDFJ Robot Surg
September 2025
Department of Urology/School of Clinical Medicine, North Sichuan Medical College/Affiliated Hospital of North Sichuan Medical College, No. 1, South Maoyuan Road, Shunqing District, Nanchong City, 63700, Sichuan Province, China.
Renal transplantation is the best option for end-stage renal disease, and in this study, patients who underwent robotic-assisted renal transplantation (RAKT) and open renal transplantation (OKT) were selected to compare their intraoperative and postoperative clinical outcomes: including Operation Time, Length of Stay, WIT (warm ischaemia time), CIT (cold ischaemia time), Estimated Blood Loss, Post 1 month Creatinine, Incision Length, Rewarming Time, Wound infection. The study was registered in PROSPERO with CRD code: CRD420251061084. We searched in Web of Science, Pubmed, Wiely, Elsevier databases, screened according to inclusion and exclusion criteria and finally included 7 papers.
View Article and Find Full Text PDFEndocr Rev
September 2025
Departments of Nutrition, Biochemistry and Molecular Medicine, University of Montreal, and Montreal Diabetes Research Center, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Glycerol and glycerol-3-phosphate are key metabolites at the intersection of carbohydrate, lipid and energy metabolism. Their production and usage are organismal and cell type specific. Glycerol has unique physicochemical properties enabling it to function as an osmolyte, protein structure stabilizer, antimicrobial and antifreeze agent, important to preservation of many biological functions.
View Article and Find Full Text PDFCirculation
September 2025
Division of Cardiology, Columbia University Irving Medical Center, New York, NY (S.A.P.).
Background: Limited treatment options exist for infrapopliteal disease in patients with chronic limb-threatening ischemia (CLTI), a condition associated with a high risk of limb loss. Interventional management of diseased infrapopliteal vessels with percutaneous transluminal angioplasty (PTA) is associated with high rates of restenosis and reintervention. In the LIFE-BTK trial, the drug-eluting resorbable scaffold (DRS) demonstrated superior 12-month efficacy compared with PTA in a selected CLTI population with predominantly noncomplex, mildly to moderately calcified lesions.
View Article and Find Full Text PDFInt J Plant Anim Environ Sci
August 2025
Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA 91766, USA.
Neurological disorders, such as Alzheimer's disease, Parkinson's disease, epilepsy, spinal cord injuries, and traumatic brain injuries, represent substantial global health challenges due to their chronic and often progressive nature. While allopathic medicine offers a range of pharmacological interventions aimed at managing symptoms and mitigating disease progression, it is accompanied by limitations, including adverse side effects, the development of drug resistance, and incomplete efficacy. In parallel, phytochemicals-bioactive compounds derived from plants-are receiving increased attention for their potential neuroprotective, antioxidant, and anti-inflammatory properties.
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