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Background: Neurosurgeons lack precise insights into the true costs of transsphenoidal endoscopic surgery for sellar and suprasellar lesions (TESS), including pituitary adenomas, craniopharyngiomas, and apoplexy. To address this critical knowledge gap, we employ time-driven activity-based costing (TDABC) for TESS.
Methods: We analyzed 221 TESS procedures performed between 2017 and 2022 at a large academic medical center. Costs were calculated using TDABC. Software was developed to extract information regarding all resources utilized intraoperatively. Supply cost was calculated as the aggregate of expenses related to implants, consumables, medications, and surgical tray sterilization. Personnel cost was determined by multiplying the per-minute wages of all intraoperative personnel by the amount of time they spent in the operating room. Patient and disease-specific variables were collected. Multivariable regression models were performed to assess predictors of cost.
Results: The average total cost of a TESS procedure was $7557 ± $2,365, with primary cost drivers being supplies ($2,811, 37%) and personnel ($4,426, 59%). On multivariable regression, factors independently associated with higher total cost were hospital site (β-coefficient: $1,028, P < 0.001), intraoperative blood loss (β-coefficient: $12, P < 0.001), length of stay (β-coefficient: $23, P = 0.015), and the use of a nasoseptal flap (β-coefficient: $731, P = 0.012). Conversely, apoplexy was associated with lower total cost (β-coefficient: $-1,149, P = 0.001), which was explained by faster operating room times and lower personnel cost (β-coefficient: $-702, P = 0.003).
Conclusions: This study represents the first application of intraoperative TDABC for transsphenoidal endoscopic surgery. Such efforts can promote value-based healthcare by identifying areas for cost reduction and surgical resource management.
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http://dx.doi.org/10.1016/j.wneu.2025.123792 | DOI Listing |
Cureus
July 2025
Department of Otolaryngology, Baylor College of Medicine, Houston, USA.
Inadvertent intracranial nasogastric tube placement is a recognized risk following skull base fracture, but prior skull base surgery also poses a significant and underrecognized risk for this potentially fatal complication. We report the case of a 75-year-old female admitted with colitis, six months after endoscopic endonasal resection of a pituitary macroadenoma. A systematic review identified 10 prior cases of intracranial tube placement following skull base or sinonasal surgery, including nasotracheal and feeding tube insertions.
View Article and Find Full Text PDFJ Neurol Surg B Skull Base
October 2025
Department of Otolaryngology - Head and Neck Surgery, Mayo Clinic Arizona, Phoenix, Arizona, United States.
Objective: The study objective was to compare the length of stay (LOS) and the proportion of one-night admissions before and after the implementation of an endocrine monitoring protocol following endoscopic transsphenoidal surgery (ETSS) for pituitary adenoma.
Methods: Patients who underwent transsphenoidal pituitary adenoma resection between July 1, 2018, and September 9, 2022, were identified, and divided into two cohorts before and after the implementation of the monitoring protocol. The overall LOS and number of nights of admission were recorded.
Quant Imaging Med Surg
September 2025
Division of Neurosurgery, Department of Neurology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, Brazil.
Neurosurg Rev
September 2025
Department of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.
The transsphenoidal approach to sellar lesions is a mainstay technique in modern neurosurgical treatment of pituitary adenomas. One prominent complication following transsphenoidal surgery is the development of postoperative hyponatremia, frequently necessitating additional medical management and hospital readmission. However, the precise incidence and risk factors of postoperative hyponatremia remain unclear in the current literature.
View Article and Find Full Text PDFLife (Basel)
August 2025
Klinik für Neurochirurgie, Klinikum Bayreuth, Medizincampus Oberfranken FAU Erlangen, 95455 Bayreuth, Germany.
Endonasal endoscopic approaches to the skull base are still under investigation, with research aiming to achieve minimally invasive procedures that maximize resection while minimizing complications. This study shares our experience with a mononostril technique and compares it with the existing literature on mononostril approaches for sellar lesions. A systematic review of eight large series, totaling 1520 patients who underwent endoscopic mononostril transsphenoidal surgery, was performed.
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