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Article Abstract
Objectives: To study compliance with national guidelines for carbapenem (CP) use.
Patients And Methods: We performed a two-year prospective monocentric and interventional study in a French university hospital. The study was based on three phases (observation (P1), intervention (P2), and post-intervention (P3)) and ended 10 months after intervention. Compliance of CP prescriptions was based on predetermined criteria.
Results: Among the 330 prescriptions assessed, treatment adequacy on Day 3 increased from 32.3 % (n = 42/130) during phase P1 to 72.2 % (n = 70/97) during phase P3 (p < 0.01), with a significant impact on indications, dosage, and duration of treatment but not on CP choice. There were no significant changes in overall CP consumption.
Conclusions: Implementing an educational antimicrobial stewardship program for hospital CP proper use had a positive impact. Educational reminders are essential to support these improvements.
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| http://dx.doi.org/10.1016/j.idnow.2025.105039 | DOI Listing |
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