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In this paper, the interaction between non-spherical bubbles is studied using a high-speed camera, and the effects of the interaction on the temperature within the bubble and the velocity of the surrounding fluid are theoretically investigated. It is found that the mean radius and the mean wall velocity of the middle bubble in three-bubble system are slightly greater than those in two-bubble system when the initial parameters are consistent. The acoustic response of the middle bubble presented a leftward shift of resonance peak and an increase of resonance peaks with increasing sound pressure. Two patterns of interactions were found in the three-bubble system: steady oscillations with slight non-spherical shape deformation, and a strong coupled state that tends to coalesce. In both patterns, the largest bubble should impose more constraints on the middle bubble, and the middle bubble was observed to be ejected towards the largest. The interacting pattern of bubbles depends on many factors, such as bubble spacing, initial radii of bubbles, acoustic frequency and intensity, which also affect the shape deformation of bubbles. Non-spherical shape deformation decreases the internal gas temperature and disturbs the flow field distribution, all of which are close to cavitation activities. Predictions of the three-bubble model are in good agreement with experimental observations, and can be used to explain bubble behaviors in chained multi-bubble systems in inertial cavitation field.
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http://dx.doi.org/10.1016/j.ultsonch.2025.107262 | DOI Listing |
BMJ Open Respir Res
September 2025
Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Background: We previously demonstrated a high prevalence of transpulmonary bubble transit (TPBT) using transcranial Doppler (TCD) in patients with COVID-19 pneumonia, but these observations require confirmation.
Methods: Patients at two academic medical centres, hospitalised with COVID-19 pneumonia and requiring any form of respiratory support, were studied. The first TCD study was performed at the time of enrolment and repeated approximately 7 and 14 days later if participants remained hospitalised.
Sci Rep
August 2025
Department of Thoracic Surgery, St. Marianna University School of Medicine, 2-16-1, Sugao, Kanagawa, Kawasaki, 216-8511, Japan.
The water submersion test (W-test) has the risk of overlooking air leaks during lung resection. We assessed the relationship between alveolar air leakage and intrathoracic gas concentrations as a novel intraoperative air leak detection method. We compared the W-test results with intrathoracic gas concentrations of desflurane, oxygen (O2), and carbon dioxide (CO2), prospectively measured using a gas analyser built-in into the anaesthesia machine before and after lung resection.
View Article and Find Full Text PDFBMC Oral Health
August 2025
Department of Periodontology, Faculty of Dentistry, Bolu Abant Izzet Baysal University, Bolu, Turkey.
Background: This study evaluates the effect of polyvinylpyrrolidone sodium hyaluronate gel (Gelclair) on palatal wound healing, pain, and bleeding following free gingival graft surgery (FGG).
Methods: Thirty-two patients undergoing FGG were randomly assigned to two groups: the test group received Gelclair and chlorhexidine mouthwash, while the control group received only chlorhexidine. Patients were called at first, third, seventh, fourteenth and twenty-eighth postoperative days and, Visual Analog Scale (VAS), Wound Healing Index (WHI), hydrogen peroxide (H₂O₂) bubbling scores and bleeding situations were recorded.
Scand J Med Sci Sports
August 2025
Division of Interventional Cardiology, University Hospital Santa Maria Alle Scotte, Siena, Italy.
Patent foramen ovale (PFO) and atrial septal defect (ASD) percutaneous closure is routinely performed. However, data on long-term safety and efficacy in athletes are lacking. This study with a long-term follow-up investigated the safety and efficacy of percutaneous PFO/ASD closure in athletes compared to non-athletes, focusing on the impact of sports participation on complications.
View Article and Find Full Text PDFAdv Sci (Weinh)
August 2025
Key Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University Provincial University, the Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, College of Life Sciences, Fujian Normal University, Fuzhou, 350117, China.
Lipid nanoparticles (LNPs) are recognized as robust and versatile drug delivery platforms holding significant promise for personalized and precision medicine applications. However, their intrinsic biological effects, including dose-limiting toxicity and acute inflammation, limit their widespread application. Elucidating the underlying mechanisms paradoxically enables dual-path optimization: targeted mitigation strategies for adverse effects and deliberate amplification of adverse effects for repurposing ("waste-to-resource").
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