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Given the widespread adoption of CBCT in clinical and research activity, it seems reasonable to critically evaluate the evidence produced on the investigations over the relationship between upper airway morphology and skeletal malocclusions patterns. The analysis method and inclusion criteria were pre-specified and documented in a protocol to minimize the risk of post hoc selective bias. A methodological quality grading system was used to identify the most valuable studies. The nine selected articles, published between 2009 and 2020, involved subjects recruited from existing databases. The average methodological quality grading assessment score was 18.6 (range: minimum 16, maximum 23). Methodological quality scores ranged from 36.1% to 63.8% of the maximum possible score, with an average quality score of 51.1%. No high-quality studies were found in the sample. This systematic review revealed that no high-quality studies have compared upper airway morphology with skeletal patterns using cone-beam computed tomography. The heterogeneity of the results did not confirm strong evidence of a direct correlation between skeletal patterns and upper airway morphology. This appears to be due to a lack of consistency in CBCT protocols.
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http://dx.doi.org/10.3390/healthcare13030208 | DOI Listing |
Elife
September 2025
Department of Earth and Environmental Sciences, Paleontology and Geobiology, Ludwig Maximilians-Universität München, Munich, Germany.
The rapid emergence of mineralized structures in diverse animal groups during the late Ediacaran and early Cambrian periods likely resulted from modifications of pre-adapted biomineralization genes inherited from a common ancestor. As the oldest extant phylum with mineralized structures, sponges are key to understanding animal biomineralization. Yet, the biomineralization process in sponges, particularly in forming spicules, is not well understood.
View Article and Find Full Text PDFJ Foot Ankle Res
September 2025
Sports Medicine and Rehabilitation Center, Shanghai University of Sport, Shanghai, China.
Objective: This study aims to investigate whether alterations in the lower extremity kinematics, kinetics, and muscle activity of individuals with chronic ankle instability (CAI) occur during landing with expected and unexpected inversion perturbations.
Methodology: PubMed, Embase, Cochrane Library, Web of Science, and Scopus databases were searched for relevant studies up to November 30, 2024. Comparative studies investigating the characteristics of lower extremity kinematics, kinetics, and muscle activity in individuals with CAI compared with healthy controls were included.
J Am Acad Orthop Surg
August 2025
From the Department of Orthopedic Surgery (Daher, Aoun, Sebaaly), Hotel Dieu de France Hospital, Beirut, LEBANON, the Department of Orthopedic Surgery (Daher, Diebo, Daniels), Brown University, Providence, RI, the Department of Orthopedic Surgery (Daher, Cottrill, Passias), Duke University, Durham,
Background: Surgical management of thoracolumbar fractures in patients with ankylosing spinal disorders such as ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis remains debated. Although several studies have compared minimally invasive surgery to open fixation of thoracolumbar fractures in this patient population, a meta-analysis compiling the literature on this topic is lacking.
Methods: Following the PRISMA guidelines, PubMed, Cochrane, and Google Scholar (pages 1 to 20) were accessed and explored until October 2024.
Am J Respir Cell Mol Biol
September 2025
University of Toronto, Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada.
Post-Intensive Care Syndrome (PICS) is a serious condition involving physical weakness, depression, and cognitive impairment that develop during or after an intensive care unit (ICU) stay, often resulting in long-term declines in quality of life. Patients with acute respiratory distress syndrome (ARDS) and severe COVID-19 are at particularly high risk, yet the molecular mechanisms underlying PICS remain poorly understood. Here, we identify impaired Apelin-APJ signaling as a potential contributor to PICS pathogenesis via disruption of inter-organ homeostasis.
View Article and Find Full Text PDFMed Sci Sports Exerc
September 2025
Department of Engineering Mechanics, Tsinghua University, Beijing, CHINA.
Purpose: Develop a musculoskeletal-environment interaction model to reconstruct the dynamic-interaction process in skiing.
Methods: This study established a skier-ski-snow interaction (SSSI) model that integrated a 3D full-body musculoskeletal model, a flexible ski model, a ski boot model, a ski-snow contact model, and an air resistance model. An experimental method was developed to collect kinematic and kinetic data using IMUs, GPS, and plantar pressure measurement insoles, which were cost-effective and capable of capturing motion in large-scale field conditions.