Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: The underlying etiologies responsible for persistent geotropic nystagmus (PGN) and apogeotropic nystagmus (PAGN) remain elusive. In this study, we analyzed the symptoms of patients with PGN and PAGN and categorize them based on diagnostic criteria for established vestibular disorders.
Methods: Clinical signs, recurrences, and duration of vestibular symptoms in patients with PGN or PAGN were collated and included auditory, neurologic, and migrainous symptoms as well as migraine history. Patients were then reclassified into unique etiological groups according to the established diagnostic criteria for vestibular disorders.
Results: Among 428 patients with nystagmus, 57 (13.3%) presented with PGN or PAGN. Of the 56 patients included in the study, 50 (89.3%) experienced a recurrence of vertigo or dizziness, and 28 (50%) had more than five episodes. Regarding the duration of symptoms, 32 patients (57.1%) experienced vestibular episodes lasting ≤ 1 day, and 46 patients (82.1%) had episodes lasting ≤ 1 week. Based on the available and accepted diagnostic categorization, 17 patients (30.4%) were diagnosed with vestibular migraine, 15 (26.8%) with probable vestibular migraine, 15 (26.8%) with benign recurrent vertigo, 3 (5.4%) with cerebellar lesions, 1 (1.8%) with sudden sensorineural hearing loss, and 5 (8.9%) with undetermined diagnoses.
Conclusions: While PGN and PAGN can be caused by various vestibular disorders, our data support the majority of cases are episodic and linked to the pathophysiology of vestibular migraine.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00415-025-12921-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Facial/sinus pain or pressure and migraine: exploratory findings from the HEADS registry.
Front Pain Res (Lausanne)
August 2025
University Otolaryngology, Providence, RI, United States.
Background: Rhinosinusitis (RS) is a leading reason for antibiotic prescriptions but treatment satisfaction is low. Misdiagnosis may contribute to poor outcomes, as migraine-often underrecognized-can mimic RS symptoms, with studies showing overlap between RS and migraine diagnoses. Our aims were to explore the demographics and clinical features of facial pain or pressure (FPP), its relationship with migraine and RS, and distinguish symptoms between these overlapping conditions.
View Article and Find Full Text PDFExploring Heterogeneity in Vestibular Migraine Using Individualized Differential Structural Covariance Network Analysis.
CNS Neurosci Ther
September 2025
Department of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Background: The high heterogeneity in vestibular migraine (VM) complicates understanding its precise pathophysiological mechanisms and identifying potential biomarkers. This study investigated the heterogeneity in VM using a newly proposed method called Individualized Differential Structural Covariance Network (IDSCN) analysis.
Methods: Structural T1-weighted MRI scans were performed on 55 patients with VM and 65 healthy controls, and an IDSCN was constructed for each patient.
[Clinical characteristics and influencing factors of vestibular migraine patients with sleep disorders].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
September 2025
Affiliated Hospital of North Sichuan Medical College，Nanchong，637000，China.
To investigate the sleep characteristics and clinical features of patients with vestibular migraine（VM）, and to explore the influencing factors of sleep disorder in VM patients. A cross-sectional study method was adopted to collect VM patients from Otolaryngology department and neurology department of our hospital from June 2022 to June 2024（divided into sleep disorder group and non-sleep disorder group according to whether there is sleep disorder） as the experimental group, and recruit non-VM volunteers with clinical characteristics matching with the experimental group during the same period as the control group. The clinical data of the subjects were collected, and the sleep quality of the subjects was assessed using the Pittsburgh Sleep Quality Index（PSQI）.
View Article and Find Full Text PDFPersonalized Diagnosis and Functional Impact of Vestibular Migraine in Women Aged 20-50: Cross-Sectional Analysis from Neurotology Clinic.
J Pers Med
August 2025
Otolaryngology, Head and Neck Surgery, Department of Surgery, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia.
: Vestibular migraine is a frequently underdiagnosed cause of dizziness in adult females, often overlapping clinically with other vestibular and neurological conditions. Despite its recognition in diagnostic criteria, limited data exist on its prevalence and functional impact in women presenting with dizziness in clinical settings. This study assesses the frequency and diagnostic rate of vestibular migraine among females aged 20-50 years presenting with dizziness and evaluates its impact on quality of life and work productivity.
View Article and Find Full Text PDFComparison of Sensory Organisation Test Results in Patients With Ménière's Disease and Vestibular Migraine: A Retrospective, Cross-Sectional Study in a Chinese Cohort.
Clin Otolaryngol
August 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Objectives: We aimed to characterise the sensory organisation test (SOT) performance and compare the posturographic difference between patients with Ménière's disease (MD) and those with vestibular migraine (VM) in the Chinese population.
Design: This cross-sectional comparative study was conducted in accordance with the STROBE guidelines.
Setting: Tertiary medical centre.