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Introduction: The present interventional, controlled, randomized, blind clinical study aimed to evaluate the effectiveness of an in-office bleaching procedure with violet LED associated or not with 37% carbamide peroxide, considering as response variables the degree of change and color stability over 12 months and dental sensitivity over a month.
Methods: Forty participants, according to the inclusion and exclusion criteria, were randomly divided into 2 groups ( = 20) according to the bleaching protocol conducted, in two sessions, with a 7-day interval: vLED-violet LED, without gel; vLED/CP-37% carbamide peroxide photocatalyzed with violet LED (control group). In the vLED group, in each session the bleaching was carried out by 2 consecutive irradiation cycles of 25' each (10 × 2' LED + 30" interval), with 5' interval between cycles. In the vLED/CP group, the gel was applied 5 times in the bleaching session and photocatalyzed 3 times for 2' with 30" intervals (7'30" per gel application), totaling 37'30" per session. Dental sensitivity was assessed using a visual analog scale (VAS) and the effectiveness of bleaching as a function of the degree of change and color stability (E) with a spectrophotometer. The data were tabulated and submitted to statistical tests ( < 0.05).
Results: The VAS analysis showed that some individuals from both groups had mild pain (1 ≤ VAS < 4) during the time intervals evaluated, being more prevalent in the vLED/CP group. Regarding the degree of color change, the groups behaved differently over time ( < 0.0001). The E observed for the vLED/CP group was superior in comparison to the vLED group at all evaluated moments.
Conclusions: Over 12 months, the vLED/CP group was more effective in relation to the bleaching effect compared to the vLED group. Both groups showed low levels of sensitivity in the studied time intervals.
Clinical Trial Registration: [https://ensaiosclinicos.gov.br/rg/RBR-6rc23h], identifier [U1111-1253-8850].
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http://dx.doi.org/10.3389/fdmed.2024.1427301 | DOI Listing |
ACS Omega
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Federal University of TechnologyParanáUTFPR, Graduate Program in Chemical and Biotechnological Processes (PPGQB), Rua Cristo Rei, 19, Vila Becker, Toledo 85902-490, Paraná, Brazil.
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Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, SP, Brazil.
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Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore560012, India.
The properties of supramolecules can be modulated by post-assembly modification (PAM) of their building blocks or via guest encapsulation. This work demonstrates a largely uncharted approach to property modulation that integrates both PAM and guest encapsulation in a single system to boost photocatalytic activity. Self-assembly of a "phenothiazine"-functionalized ligand () with a -blocked Pd(II) acceptor () generated an trifacial tube ().
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Department of Microbiology, Key Laboratory for Experimental Teratology of the Ministry of Education, School of Basic Medical Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China. Electronic address:
Biofilm formation represents a critical survival strategy for Helicobacter pylori (H. pylori), facilitating antibiotic resistance and chronic colonization. In this study, we demonstrate that reactive oxygen species (ROS) released by macrophages enhance H.
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