High-Gradient "Moderate" Aortic Stenosis: Is it Moderate or Severe?

JACC Cardiovasc Imaging

Department of Cardiology, Houston Methodist Hospital and The DeBakey Heart and Vascular Center, Houston, Texas, USA. Electronic address:

Published: February 2025


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcmg.2024.10.013DOI Listing

Publication Analysis

Top Keywords

high-gradient "moderate"
4
"moderate" aortic stenosis
4
aortic stenosis moderate
4
moderate severe?
4
high-gradient
1
aortic stenosis
1
moderate
1
severe?
1

Similar Publications

Background: Management of transcatheter aortic valve replacement (TAVR) in aortic stenosis (AS) flow-groups-high-gradient (HG-AS), classical low-flow low-gradient (cLFLG-AS), and paradoxical low-flow low-gradient (pLFLG-AS)-is debated. Concomitant mitral regurgitation (MR) worsens outcomes, but the influence of MR etiology on AS subtypes is unclear.

Aims: To evaluate the impact of MR etiology and severity on outcomes across AS flow groups in TAVR patients.

View Article and Find Full Text PDF

Purpose: Patients with aortic stenosis (AS) may have discordant severity grades between AS by aortic valve area (AS) and AS using hemodynamic-based guidelines (AS). Individuals with normal left ventricular function and normal-flow low-gradient (NF-LG) AS that is moderate or severe by AVA are downgraded in severity by current guidelines. We evaluated the prevalence and risk of NF-LG AS in patients with moderate or severe AS.

View Article and Find Full Text PDF

Aims: This study aims to describe the prevalence of discordant mild/moderate aortic stenosis (AS) in a population-based study and to identify the mechanisms that lead to reduced stroke volume (SV) and discordant moderate AS.

Methods And Results: Discordant high-gradient (HG)-mild AS, defined as AVA > 1.5 cm2 and mean pressure gradient (MG) of 20-40 mmHg, and discordant low-gradient (LG) moderate AS, defined as AVA 1.

View Article and Find Full Text PDF

This study sought to explore the clinical factors associated with classical low-flow low-gradient (C-LFLG) and normal-flow low-gradient (NFLG) aortic stenosis (AS) compared with high-gradient (HG) AS. We also compared clinical and echocardiographic outcomes after transcatheter aortic valve replacement (TAVR) across flow-gradient patterns. Patients with C-LFLG AS have a higher mortality rate after TAVR than those with HG AS.

View Article and Find Full Text PDF