Publications by authors named "Odette Iskandar"
Background: Leaflet thrombosis and transcatheter heart valve dysfunction are key concerns following transcatheter aortic valve replacement (TAVR). Prolonged neo-sinus washout time (NWT) may predispose patients to hypoattenuated leaflet thickening (HALT) and leaflet thrombosis, increasing the risk of valve degeneration. This study evaluates the association between in vivo NWT derived from aortograms using computer vision and hemodynamic outcomes at 30 days and 1 year post-TAVR.
View Article and Find Full Text PDFAortic Root Anatomy and Impact on New-Onset Left Bundle Branch Block After Transcatheter Aortic Valve Implantation.
Catheter Cardiovasc Interv
May 2025
Background: Angulation of virtual basal ring (VBR), also known as aortic annulus, in relation to sino-tubular junction (STJ) may lead to greater exposure of implanted stent to the conduction system, consequently increasing the risk of left bundle branch block (LBBB).
Aims: We sough to measure the VBR-STJ angle and explore its impact on the development of LBBB post-TAVR.
Methods: Patients undergoing TAVR using the Sapiens 3 valve between 2016 and 2021, without pre-TAVR conduction anomalies were included.
This study sought to explore the clinical factors associated with classical low-flow low-gradient (C-LFLG) and normal-flow low-gradient (NFLG) aortic stenosis (AS) compared with high-gradient (HG) AS. We also compared clinical and echocardiographic outcomes after transcatheter aortic valve replacement (TAVR) across flow-gradient patterns. Patients with C-LFLG AS have a higher mortality rate after TAVR than those with HG AS.
View Article and Find Full Text PDFBackground: Data supporting the use of transcatheter aortic valve replacement (TAVR) for bicuspid aortic valve (BAV) is limited compared to tricuspid aortic valve (TAV) anatomy, as the BAV anatomy poses unique challenges to prosthesis expansion and symmetric deployment.
Aims: We aim to compare the acute recoil and asymmetry of the SAPIEN-3 valve between BAV and TAV anatomies and their impact on procedural outcomes.
Methods: We conducted a single-center study of patients who underwent TAVR with the SAPIEN-3 valve.
Article Synopsis
- The popularity of atrial catheter ablation has surged as a leading treatment for supraventricular tachycardias, praised for its safety and effectiveness.
- Complications can occur at various stages, including vascular, thromboembolic, and mechanical issues, with atrial fibrillation ablation being notably riskier due to its complexity.
- Strategies to minimize risks involve advanced techniques like optimized anticoagulation and esophageal temperature monitoring, while emerging methods like pulsed-field ablation show promise for improved safety, pending further research.