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Purpose: Conventional MRI coils offer suboptimal parallel imaging performance for young children. Our goal was to enhance imaging acceleration by dedicated, flexible high-density coil design for pediatric patients at 3T.
Methods: We design, construct, and evaluate a highly flexible small loop array. Key design notes include full-wave simulation and analysis of the dual-turn loop, miniature feedboard allocation at the loop center, and cable management. Phantom experiments and adult and pediatric volunteer case studies were conducted to evaluate the small loop array imaging performance compared to commercial reference coils.
Results: Dual-turn loop configuration forms higher preamp decoupling impedance than the same size single-turn, supporting a flexible form factor that requires a wide range of critical overlap. Both phantom and in-vivo studies demonstrate superior parallel imaging performance or high spatial resolution imaging using the small loop, compared to commercial reference coils.
Conclusion: A dedicated high-density coil array with a minimum inter-component interference layout design allows a flexible form factor and higher imaging accelerations. Phantom and in-vivo volunteer case studies demonstrate promising results in improving efficiency for pediatric patients in routine clinical imaging procedures.
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http://dx.doi.org/10.1002/mrm.30456 | DOI Listing |
Mol Pharm
September 2025
Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Tissue factor (TF) has emerged as a promising target for the diagnosis and treatment of hepatocellular carcinoma (HCC). However, there is limited data available on TF-related PET imaging for longitudinal monitoring of the pathophysiological changes during HCC formation. Herein, we aimed to explore the TF-expression feature and compare a novel TF-targeted PET probe with F-FDG through longitudinal imaging in diethylnitrosamine (DEN)-induced rat HCC.
View Article and Find Full Text PDFRetina
September 2025
Ulucanlar Eye Training and Research Hospital, Retina Clinic of Ophthalmology Department, Ankara, Turkey.
Purpose: To compare the clinical features, multimodal imaging characteristics, and treatment outcomes of primary and secondary large retinal capillary aneurysms (LRCA).
Methods: A total of 34 eyes were included: seven with primary LRCA and 27 with secondary LRCA. All patients underwent fundus photography, optical coherence tomography (OCT), and fundus fluorescein angiography.
Menopause
September 2025
Department of Obstetrics and Gynecology, Gaziantep University School of Medicine, Gaziantep, Turkey.
Objective: Our study aimed to compare premenopausal and postmenopausal women in terms of choroidal thickness and choroidal vascularity index.
Methods: This cross-sectional study included 96 eyes of 96 participants, comprising 48 premenopausal and 48 postmenopausal women. Enhanced depth image optical coherence tomography (EDI-OCT) was used to visualize the choroid.
Menopause
September 2025
Department of Speech Language Pathology and Audiology, Northeastern University, Boston, MA.
Importance And Objective: Voice changes during menopause affect patients' communication and quality of life. This narrative review aims to provide a comprehensive exploration of voice changes during menopause. It presents objective and subjective/symptomatic changes as well as treatment options for this population.
View Article and Find Full Text PDFEur J Endocrinol
September 2025
Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, 55905.
Objective: Identify social/metabolic risk factors associated with subsequent diagnosis of adrenal adenoma.
Design: Population-based historical case-control study.
Methods: Cases were adult patients diagnosed with an adrenal adenoma between 2005-2017 with no overt hormone excess.