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Background: Oral cancer (OC) is the sixth most common cancer worldwide. There have been few studies on OC in high-risk populations. This study aimed to describe the clinical features, staging, grading, and risk factors in OC patients.
Methods: This cross-sectional study was conducted on 109 OC patients diagnosed and treated from April 2018 to May 2020. The patients were identified using eData.
Results: The average age of the patients was 60.32 ± 12.4 years, and the male-to-female ratio was 2.9:1. The most common site for OC was the tongue (37.6%), and oral squamous cell carcinoma was the most common histopathology (84.4%). The most common clinical forms were verruca (37.6%) and erosive ulcers (33.9%). Most patients were in stage III or IV (71.6%). Average time of detection was 7.32 ± 17.12 months.
Conclusions: OC occurs most often in elderly people, males, and is diagnosed late. The main risk factors are smoking and consuming alcohol.
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http://dx.doi.org/10.1007/s12663-023-01997-2 | DOI Listing |
BMC Oral Health
September 2025
Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Background: A modified pull-through approach represents a promising treatment strategy to access tumors in the posterior oral cavity. The design of the wedge osteotomy plays a key role in preserving postoperative mechanical stability while enabling surgical access. However, the optimal osteotomy design to reduce fracture risk remains unclear.
View Article and Find Full Text PDFOral Maxillofac Surg
September 2025
Department of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Shinmachi 2-5-1, Hirakata-city, Osaka, Japan.
Purpose: For submandibular gland resection, conventional surgery with the naked eye remains the standard. With its excellent automatic focus and high magnification, the ORBEYE 3D exoscope enables precise submandibular gland resection with less stress. Therefore, we aimed to examine the usefulness of the exoscope in submandibular gland resection.
View Article and Find Full Text PDFNat Aging
September 2025
Aging Biomarker Consortium (ABC), Beijing, China.
The global surge in the population of people 60 years and older, including that in China, challenges healthcare systems with rising age-related diseases. To address this demographic change, the Aging Biomarker Consortium (ABC) has launched the X-Age Project to develop a comprehensive aging evaluation system tailored to the Chinese population. Our goal is to identify robust biomarkers and construct composite aging clocks that capture biological age, defined as an individual's physiological and molecular state, across diverse Chinese cohorts.
View Article and Find Full Text PDFBr J Cancer
September 2025
Institute of Life Sciences, Bhubaneswar, Odisha, India.
Background: Docetaxel is the most common chemotherapy regimen for several neoplasms, including advanced OSCC (Oral Squamous Cell Carcinoma). Unfortunately, chemoresistance leads to relapse and adverse disease outcomes.
Methods: We performed CRISPR-based kinome screening to identify potential players of Docetaxel resistance.
Oral Oncol
September 2025
Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 602105, India. Electronic address: