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Around 25%-40% of ischemic strokes are cryptogenic, with no identifiable cause despite thorough evaluation. The mechanisms behind cryptogenic strokes are often embolic, frequently originating from occult cardiac sources. An unroofed coronary sinus (UCS), a rare congenital anomaly, involves a partial or complete absence of the coronary sinus roof, leading to a connection between the left atrium and the coronary sinus. This defect can be asymptomatic or present with symptoms such as paradoxical embolism due to shunting. We present the case of a 70-year-old male with prolonged chest pain and a history of neurological symptoms, who was later diagnosed with a UCS (types III and IV) through cardiac computed tomography (CCT). A cardiac bubble test confirmed a right-to-left shunt, which was not detected on transthoracic echocardiography. This case underscores the importance of considering advanced imaging techniques such as CCT in the diagnosis of cryptogenic stroke, as echocardiography may miss defects due to poor visualization of posterior cardiac structures.
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http://dx.doi.org/10.4103/jcecho.jcecho_57_24 | DOI Listing |
Medicine (Baltimore)
September 2025
Department of Intensive Care Unit, The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, Foshan Hospital of Traditional Chinese Medicine, Foshan City, Guangdong Province, China.
Rationale: Mental and behavioral abnormalities are difficult neurological conditions, and the site of the lesion may involve the basal ganglia. Its etiology is varied and requires a detailed differential diagnosis.
Patient Concerns: An 81-year-old woman had a history of "cerebral infarction" for 5 years.
Front Cardiovasc Med
August 2025
Department of Cardiovascular Surgery, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Introduction: Left ventricular assist device (LVAD) implantation is a highly effective procedure for the management of selected advanced heart failure patients, prolonging patient life and improving quality. Additional cardiac pathologies, especially valvular regurgitation or coronary heart disease, are common in LVAD recipients, whereas reports on the surgical management of heart failure combined with aortic disease are rare.
Case Presentation: We present a case of a 60-year-old patient with an aortic sinus aneurysm, aortic regurgitation, and end-stage heart failure.
Am J Cardiol
September 2025
Tel Aviv Medical Center, 6 Weizmann St, Tel Aviv, 6423906, Israel. Electronic address:
Effective therapy for patients suffering from refractory angina remains a major unmet need. Chronic angina, which is refractory to medical and interventional therapies, affects patients who are not suitable for revascularization, patients following successful revascularization, and patients with coronary microvascular dysfunction. Coronary sinus (CS) narrowing has been studied as a potential therapy for patients with angina.
View Article and Find Full Text PDFJACC Case Rep
September 2025
Meyer University Hospital, Florence, Italy.
Background: Single coronary artery is a rare congenital anomaly. Its coexistence with coronary artery fistula is exceedingly uncommon.
Case Summary: A 61-year-old woman with no cardiovascular risk factors underwent her first cardiological evaluation after incidental detection of atrial fibrillation.
Acta Cardiol
September 2025
Department of Ultrasound, Wuhan Asia Heart Hospital, Affiliated Wuhan University of Science and Technology, Wuhan Clinical Medical Research Center of Cardiovascular Imaging, Wuhan City, Hubei Province, P.R. China.