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Purpose: Owing to the time-sensitive nature of myocardial ischemia, challenging clinical scenarios should be considered in patients with type A acute aortic dissection (AAAD) complicated by coronary malperfusion. In clinical settings, the diagnosis and reperfusion strategies for coronary malperfusion often depend on institutional resources. This study evaluated early surgical outcomes in such patients, focusing on transportation type and clinical management.
Methods: We retrospectively reviewed 70 patients who underwent emergency surgery for AAAD with coronary malperfusion, excluding those with cardiac tamponade on arrival, between 1997 and February 2024. Patients were divided into 2 groups based on transportation: direct transfer and referral.
Results: Overall, in-hospital mortality was 27%, with only 1 of 9 patients surviving with preoperative peripheral extracorporeal membrane oxygenation (ECMO). Mortality and morbidity did not significantly differ between groups. Univariate analysis identified left coronary artery involvement and preoperative hemodynamic instability as significant risk factors. Additionally, preoperative diagnostic-only coronary angiography (CAG) with unsuccessful reperfusion was a potential risk factor (P = 0.06).
Conclusions: Regardless of transportation type, preoperative peripheral ECMO itself could not be a definitive solution in AAAD patients with coronary malperfusion. Also, patients who underwent preoperative CAG with unsuccessful reperfusion might be fatal, especially with suspected left coronary artery involvement.
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http://dx.doi.org/10.5761/atcs.oa.24-00182 | DOI Listing |
Background: This study aimed to validate the predictive performance of the GERAADA (German Registry for Acute Type A Aortic Dissection) score in predicting 30-day mortality rate in patients with acute type A aortic dissection in China.
Methods: We retrospectively analyzed 526 patients who underwent surgical treatment for acute type A aortic dissection at our institution between 2018 and 2021. The predictive performance of the GERAADA score was evaluated using calibration (observed-to-expected ratio and Hosmer-Lemeshow test) and discrimination (area under the receiver operating characteristic curve).
J Cardiothorac Surg
August 2025
Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at UTHealth Houston, 6400 Fannin St, Ste. #2850, Houston, TX, 77030, USA.
Objectives: We analyzed our data to evaluate the safety and feasibility of intraoperative extracorporeal membrane oxygenation and intra-aortic balloon pump use in acute type A aortic dissection repair.
Methods: Between December 1999-December 2020, we identified patients who received intraoperative extracorporeal membrane oxygenation and/or intra-aortic balloon pump support to wean off cardiopulmonary bypass were retrospectively reviewed.
Results: A total of 690 patients who underwent acute type A dissection repair.
Eur J Cardiothorac Surg
August 2025
Department of Cardiovascular Surgery, University Hospital Giessen, Medical Faculty Justus-Liebig-University, Giessen, Germany.
Objectives: The "German Registry for Acute Aortic Dissection Type A" (GERAADA) long-term follow-up firstly investigates the neurologic outcomes over a 16-year timeframe and secondly determines whether acute Stanford type A aortic dissection (ATAAD) patients are at risk for secondary neurologic complications.
Methods: Thirty-three centers provided follow-up data of 2,686 individuals. Of those, 814 provided long-term data regarding their neurological status and incidence of stroke.
Eur J Cardiothorac Surg
January 2022
Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 10037, China.
Objectives: This study aimed to analyse how different indications for coronary artery bypass grafting (CABG) impact early mortality and long-term outcomes in patients with acute type A aortic dissection at a single high-volume centre.
Methods: Between 2010 and 2018, patients diagnosed with acute type A aortic dissection who underwent emergency surgical repair at Fuwai Hospital were included. Patients were categorized by presence of concomitant CABG.
Placenta
August 2025
La Paz University Hospital, Pathology Department, Madrid, Spain.
Introduction: Breus' mole, or massive subchorionic thrombohematoma (MST), is an exceedingly rare placental condition associated with adverse pregnancy outcomes. We aim to describe the clinical, ultrasonographic, and histopathological features of newly diagnosed MST cases and review those previously reported.
Materials And Methods: We conducted a retrospective observational study of MST cases diagnosed between 2016 and 2024 in two Spanish referral hospitals for high-risk pregnancies.