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As an important tool for the surgical treatment of pelvic floor dysfunction, the safety of mesh must be guaranteed. Although the short-term curative effect of most synthetic mesh is satisfactory, complications often occur due to its material. Planting stem cells on mesh through specific methods may resolve the problems of mesh with poor biocompatibility or an uncontrollable rate o degradation. Based on recent research, this paper summarizes the research progress of stem cells composited with common mesh materials, such as polypropylene, polylactic acid and acellular matrix.
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http://dx.doi.org/10.1016/j.ejogrb.2025.01.018 | DOI Listing |
Int Urogynecol J
September 2025
Health Sciences Faculty, Department of Physiotherapy and Rehabilitation, Izmir Katip Celebi University, Izmir, Türkiye.
Introduction And Hypothesis: To translate and perform cultural adaptation of the Pelvic Floor Dysfunction-SENTINEL (PFD-SENTINEL) screening tool into Turkish and to establish its reliability and validity for female athletes.
Methods: The study included 200 female athletes (mean age 22 ± 4 years). The translation of the PFD-SENTINEL, which comprised the symptoms related to PFD and item sections related to general risk factors and sports-related risk factors, was performed in accordance with international recommendations.
Autophagy
September 2025
Department of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Immune checkpoint inhibitors (ICIs) can re-active the immune response and induce a complete response in mismatch repair-deficient and microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC). However, most CRCs exhibit proficient mismatch repair and microsatellite stable (pMMR/MSS) phenotypes with limited immunotherapy response because of sparse intratumoral CD8 T-lymphocyte infiltration. Cellular senescence has been reported to involve immune cell infiltration through a senescence-associated secretory phenotype (SASP).
View Article and Find Full Text PDFNeurourol Urodyn
September 2025
Laboratório de Biomecânica, Centro de Ciências da Saúde e do Esporte (CEFID), Universidade do Estado de Santa Catarina (UDESC), Florianópolis, Brazil.
Aims: This study aimed to investigate the prevalence of urinary incontinence (UI) among Brazilian female triathletes and to identify associated factors, focusing on demographic, obstetric, and sports-related variables.
Methods: A cross-sectional study was conducted with 90 female triathletes. Data on age, body mass index (BMI), pregnancy history, parity, delivery type, training frequency, and weekly training volume were collected through in-person interviews and an online questionnaire.
Int Urogynecol J
September 2025
Dr. D.Y. Patil Vidyapeeth (Deemed to be University), Pimpri, Pune, Maharashtra, India.