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To better understand how the biocatalyzed depolymerization of polyesters works, model molecules are needed to develop activity assays and determine enzymatic kinetic parameters. In this communication the chemical synthesis and characterization of 2-hydroxyethyl furan-5-carboxylic acid and bis(2-hydroxyethyl) furan-2,5-dicarboxylates as potential model molecules to further study the enzymatic depolymerization of poly(ethylene furanoate) was investigated.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7617567 | PMC |
http://dx.doi.org/10.1002/open.202400507 | DOI Listing |
ChemistryOpen
August 2025
Dipartimento di Chimica e Chimica Industriale, Università degli Studi di Genova, Via Dodecaneso 31, 16146, Genova, Italy.
To better understand how the biocatalyzed depolymerization of polyesters works, model molecules are needed to develop activity assays and determine enzymatic kinetic parameters. In this communication the chemical synthesis and characterization of 2-hydroxyethyl furan-5-carboxylic acid and bis(2-hydroxyethyl) furan-2,5-dicarboxylates as potential model molecules to further study the enzymatic depolymerization of poly(ethylene furanoate) was investigated.
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