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BACKGROUND As the population ages, comorbidities among elderly patients are becoming a significant problem, due to associated risks and mortality. Medication adherence is crucial for controlling chronic diseases and improving patient outcomes; therefore, it is important to understand medication adherence among hospitalized patients. MATERIAL AND METHODS A cross-sectional study was conducted from June 2023 to April 2024 in 2 tertiary hospitals in Wuhu City, Anhui Province, China. Patients were divided into 2 age groups: 45 to 60 years and over 60 years. Data were collected using a self-designed sociodemographic questionnaire, the 4-item Morisky Medication Adherence Scale (MMAS-4), frailty scale, social frailty scale, and subjective cognitive decline questionnaire 9 (SCD-Q9). RESULTS A total of 963 inpatients were recruited, with 18.0% being middle-aged and 82.0%, elderly. The prevalence of medication adherence was 50.2%. Univariate analysis showed that medication adherence was significantly associated with place of residence, having relatives as medical personnel, physical frailty, social frailty, and subjective cognitive symptoms. Correlation analysis revealed that medication adherence was significantly negatively correlated with physical frailty, social frailty, and subjective cognitive symptoms. Binary logistic regression confirmed significant associations between medication adherence and physical frailty, social frailty, and subjective cognitive symptoms. CONCLUSIONS This study investigated medication adherence and its influencing factors among hospitalized patients with comorbidities in Anhui Province, China, identifying several influencing factors. Therefore, targeted interventions should be implemented by the government and relevant departments to improve patients' medication adherence.
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http://dx.doi.org/10.12659/MSM.945805 | DOI Listing |
J Multidiscip Healthc
September 2025
School Public Health and Social Work, Faculty of Health, Queensland University of Technology, Brisbane, QLD, Australia.
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July 2025
Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Problem-solving therapy (PST) is a brief psychological intervention often implemented for depression. Currently, there are no tools with well-evidenced reliability to measure PST fidelity. This pilot study aimed to measure the inter-rater reliability and agreement of the blem-Slving Therapy idelity (PROOF) scale, comprising binary 14-item adherence and an 8-item competence subscales.
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August 2025
Nursing Department, The First Affiliated Hospital of Ningbo University, 315000 Ningbo, Zhejiang, China.
Background: To explore the potential categories of compliance development track of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS) using growth mixture modeling (GMM) to analyze its predictive factors, providing evidence for dynamic adherence monitoring and tailored interventions.
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Scand J Caring Sci
September 2025
Lab3R - Respiratory Research and Rehabilitation Laboratory, School of Health Sciences (ESSUA) and Institute of Biomedicine (iBiMED), University of Aveiro, Aveiro, Portugal.
Background: Cystic fibrosis imposes a significant treatment burden on children and their informal caregivers, who have to change their routines to carefully adhere to medication and exercise as treatment regimes. Although informal caregivers are known to be key players in the daily management of these children, their own voice is scarcely explored, often hindering personalisation of care. The main objective of the study was to map the multifactorial impact of cystic fibrosis, as well as identify barriers and facilitators perceived by parental caregivers in managing the disease in the paediatric age.
View Article and Find Full Text PDFCurr Hypertens Rev
September 2025
Department of Pharmacology, Mediciti Institute of Medical Sciences, Ghanpur, Telangana, India.
Introduction: Hypertension is a major contributor to disability-adjusted life years (DALYs) worldwide, as highlighted by the Global Burden of Disease study (GBD 2021). Effective management of hypertension through medication can significantly lower the risks associated with the condition. It is important to recognize that not adhering to antihypertensive therapy often leads to negative health outcomes.
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