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Firefighters are exposed to the risk of burns at fire scenes. In 2020, the National Fire Agency of the Republic of Korea surveyed 50,527 firefighters and identified 242 burn-related incidents. The body parts affected by these burns were the hands (28.51%), ears (10.74%), and neck (10.33%), with hands and facial areas accounting for ∼50% of all burns. This trend implies that gloves and hoods do not provide sufficient protection against burns. Firefighters alternate between activity and rest during firefighting operations to enhance mission efficiency. However, the accumulated heat in their hood and gloves from these repeated cycles has not been considered thus far. This study investigated thermal accumulation patterns based on the moisture content of hoods and gloves, reflecting repeated cycles of work and rest for firefighters. Consequently, heat accumulation occurred in a dry state in both the hood and gloves, and the degree of heat storage was higher in the hood. The glove stored heat even when wet because of its multilayer structural characteristics. These results suggest that repeated activities (work-rest) with gloves and hoods under dry/wet conditions can generate residual heat and heat accumulation, causing burns on the hand and face. This study clearly demonstrated the impact of the moisture conditions of gloves and hoods in repetitive situations where they are exposed to relatively low levels of heat radiation and are then subject to rest periods. The results of this study are expected to be valuable in designing new protective gear to prevent burn injuries and developing efficient firefighting tactics.
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http://dx.doi.org/10.1177/00368504251315803 | DOI Listing |
Biomater Sci
September 2025
Department of Pharmaceutics and Pharmaceutical Technology, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates.
Colorectal cancer (CRC) remains a major global health burden, necessitating more effective and selective therapeutic approaches. Nanocarrier-based drug delivery systems offer significant advantages by enhancing drug accumulation in tumors, reducing off-target toxicity, and overcoming resistance mechanisms. This review provides a comprehensive overview of recent advancements in nanocarriers for CRC therapy, including passive targeting the enhanced permeability and retention (EPR) effect, and active targeting strategies that exploit specific tumor markers using ligands such as antibodies, peptides, and aptamers.
View Article and Find Full Text PDFTemperature (Austin)
June 2025
Kanto Golf Association, Chuo-ku, Tokyo, Japan.
The associated factors for exertional heat stroke among amateur golfers remain poorly understood. We conducted a case-control study to examine exertional heat exhaustion (EHE) - related symptoms among amateur golfers in Japan using a self-administered questionnaire. Retrospective case-control study design.
View Article and Find Full Text PDFAm J Bot
September 2025
Research Unit Modeling Nature, Universidad de Granada, Granada.
Premise: Floral pigments primarily serve to attract pollinators through color display and also contribute to protection against environmental stress. Although pigment composition can be plastically altered under stress, its impact on pollinator color perception remains poorly understood. Moricandia arvensis (Brassicaceae) exhibits seasonal floral dimorphism, with lilac spring flowers and white summer flowers.
View Article and Find Full Text PDFBiomed Pharmacother
September 2025
Department of Biomedical Sciences, Institute of Health, Jimma University, Jimma 378, Ethiopia; Division of Research & Development, Lovely Professional University, Phagwara 144411, India. Electronic address:
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterised by cognitive decline and the accumulation of misfolded proteins, including amyloid-beta and hyperphosphorylated tau, which impair neuronal function and promote cell death. These misfolded proteins disrupt proteostasis by forming toxic aggregates that exacerbate disease progression. Molecular chaperones, such as heat shock proteins, actively maintain protein homeostasis by assisting in proper folding, preventing aggregation, and promoting the clearance of misfolded proteins.
View Article and Find Full Text PDFPlant Cell
September 2025
Department of Plant Sciences, College of Biological Sciences, State Key Laboratory of Plant Environmental Resilience, China Agricultural University, Beijing 100193, China.
Plant thermomorphogenesis is a critical adaptive response to elevated ambient temperatures. The transcription factor PHYTOCHROME-INTERACTING FACTOR 4 (PIF4) integrates diverse environmental and phytohormone signals to coordinate thermoresponsive growth. However, the cellular mechanisms underlying plant thermomorphogenic growth remain poorly understood.
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