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The corpus callosum is a large subcortical white matter region in the brain that contains fiber connecting both cerebral hemispheres together; it has a rich blood supply; hence, infarction in this region is rare. There are a few reported cases of corpus callosal infarction, and here we present our patient who had a clinical presentation that was not suggestive of corpus callosal infarction. However, an MRI brain confirmed the location, and the patient was managed following the standard stroke treatment, and vascular risk factors were addressed and managed.
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http://dx.doi.org/10.7759/cureus.75984 | DOI Listing |
J Neurooncol
September 2025
Department of Radiation Oncology, Massachusetts General Hospital, Boston, USA.
Purpose: Cranial irradiation is associated with health-related quality of life (HRQoL) deficits in childhood cancer survivors. We investigated the relationship between radiation dose to brain substructures and HRQoL in children with brain tumors treated with proton beam therapy (PBT).
Methods: Data were obtained from children in the Pediatric Proton/Photon Consortium Registry who received PBT for primary brain tumors between 2015 and 2021.
Neurol Res
September 2025
Department of Human Anatomy, Wannan Medical College, Wuhu, China.
Background: Ischemic stroke can damage the cerebral white matter, resulting in myelin loss and neurological deficits. Moreover, microglial activation plays an important role in ischemic stroke; therefore, inhibiting microglial activation has become an effective therapeutic target for ischemic stroke.
Objective: This study aimed to investigate the effects of electroacupuncture (EA) on microglial activation and polarization, and the role of oligodendrocyte genesis in myelin reformation after ischemic stroke.
J Korean Med Sci
September 2025
Department of Neurosurgery, Korea University Anam Hospital, College of Medicine, Korea University, Seoul, Korea.
Background: Alzheimer's disease (AD) and vascular dementia (VaD) have distinct pathognomonic features, but they frequently co-occur as mixed dementia (MD) in elderly adults. This study aimed to develop a novel MD mouse model using bilateral carotid artery stenosis (BCAS) in 5 times familial Alzheimer's disease (5xFAD) transgenic mice and characterize its behavioral and histological features.
Methods: Thirteen C57BL/6 and sixteen 5xFAD transgenic mice were prepared.
Aim: Hydrocephalus is a condition characterized by the excessive accumulation of cerebrospinal fluid in the brain's ventricular system, leading to ventricular enlargement and increased intracranial pressure. This study aimed to evaluate whether transfontanel ultrasonography could serve as a practical and less complex alternative to brain magnetic resonance imaging in infants with hydrocephalus.
Material And Methods: In this prospective study, 54 infants diagnosed with hydrocephalus underwent both transfontanel ultrasonography and brain magnetic resonance imaging.
Cureus
August 2025
Neurological Surgery, Punjab Institute of Neurosciences, Lahore, PAK.
Parvovirus B19 (PVB19) is an infrequent, serious, yet treatable cause of infection in immunocompromised hosts. Neurological manifestations of PVB19 are encephalitis, encephalopathy, meningitis, cerebellar ataxia, transverse myelitis, stroke, and peripheral neuropathy. The objective is to identify the exact clinical and diagnostic features specific to parvovirus B19 encephalitis for the isolation and management of the pathology.
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