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http://dx.doi.org/10.1007/s00604-024-06919-8 | DOI Listing |
IEEE J Biomed Health Inform
September 2025
Drug-target interaction (DTI) identification is of great significance in drug development in various areas, such as drug repositioning and potential drug side effects. Although a great variety of computational methods have been proposed for DTI prediction, it is still a challenge in the face of sparsely correlated drugs or targets. To address the impact of data sparsity on the model, we propose a multi-view neighborhood-enhanced graph contrastive learning approach (MneGCL), which is based on graph clustering according to the adjacency relationship in various similarity networks between drugs or targets, to fully exploit the information of drugs and targets with few corrections.
View Article and Find Full Text PDFCell Tissue Bank
September 2025
Medline Hospital, Adana, Turkey.
To evaluate long‑term outcomes of corneal patch grafting (CPG) and to determine prognostic factors for anatomical and functional success. This retrospective study included 35 eyes from 35 patients who underwent CPG between April 2016 and September 2022 at Adana City Training and Research Hospital. Collected data included age, sex, preoperative and postoperative best-corrected visual acuity (BCVA), graft localization and size, anterior segment findings, graft survival, secondary surgical procedures, and rates of anatomical and functional success.
View Article and Find Full Text PDFPalliat Med Rep
June 2025
Dartmouth Geisel School of Medicine, Missoula, Montana, USA.
The field of hospice and palliative care in the United States is experiencing serious problems and faces an uncertain future. Quality of hospice care is highly variable. Unethical hospice business practices are common in some regions.
View Article and Find Full Text PDFJ Comput Soc Sci
September 2025
Chair of Research Methods in Developmental and Educational Sciences, Institute of Education, University of Zurich, Zurich, Switzerland.
School curricula guide the daily learning activities of millions of students. They embody the understanding of the education experts who designed them of how to organize the knowledge that students should acquire in a way that is optimal for learning. This can be viewed as a learning 'theory' which is, nevertheless, rarely put to the test.
View Article and Find Full Text PDFNAR Genom Bioinform
September 2025
Research Group for Genomic Epidemiology, National Food Institute, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Advances in Oxford Nanopore Technologies (ONT) with the introduction of the r10.4.1 flow cell have reduced the sequencing error rates to <1%.
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