Effect of microemulsion system on water dispersibility and bioavailability of γ-oryzanol.

Biosci Biotechnol Biochem

Laboratory of Food Function Analysis, Graduate School of Agricultural Science, Tohoku University, Miyagi, Japan.

Published: March 2025


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Article Abstract

This study developed water-dispersible γ-oryzanol (WD-OZ) using a microemulsion system and assessed their absorption in rats. While OZ itself is hardly soluble in water, WD-OZ exhibited high water dispersibility, and OZ, along with its metabolites, was detected in rat plasma. These findings provide a solid basis for future application of the microemulsion-based approach to enhance the bioavailability of OZ in food.

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http://dx.doi.org/10.1093/bbb/zbaf002DOI Listing

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