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Introduction: The number of vertical artefacts (VAs) in lung ultrasound (LUS) impacts patients' clinical management. This study aimed to demonstrate the influence of ultrasound settings on the number of VAs in patients under invasive mechanical ventilation (IMV).
Methods: Patients under IMV were recruited for LUS, including three breathing cycles with a motionless curvilinear probe on the thoracic region with the most VAs. Three experts in LUS were asked about the number of VAs at random, and blinded after altering the settings for a total of 20 test recordings per patient. The correlation between expert classifications was tested after grading the classifications. The number of VAs across clinicians was compared between baseline recordings and test condition recordings to determine statistical differences.
Results: 29 patients were enrolled with a median Sequential Organ Failure Assessment score of 6 (interquartile range (IQR) 3). IMV was mainly due to stroke (n=10) and pneumonia (n=6). LUS was made between days 1 and 6 (IQR). Baseline recordings showed a median of 2±2 VAs in inspiration and a median of 1±2 in expiration from a total of 3636 expert classifications, with a strong agreement within patients. A probe frequency of 8 MHz, artefact filtering, speckle reduction and frame average reduced the median VA number by one. A power of -20 dB and dynamic range of 32 dB abolished the VAs. A gain above 90% increased the median number of VAs by one.
Conclusion: In this study, the LUS settings influenced the VA number in IMV patients, after controlling for physiological and operator confounders.
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http://dx.doi.org/10.1183/23120541.00483-2024 | DOI Listing |
Clin Oral Investig
September 2025
Department of Endodontics, Faculty of Dentistry, Galala University, Suez, Egypt.
Objectives: Postoperative pain remains a significant concern in endodontics. The main aim of this clinical trial was to assess the impact of various obturation technique and sealer types on post-obturation pain and sealer extrusion in single-visit nonsurgical root canal treatments.
Materials And Methods: Study participants were recruited through consecutive sampling from patients referred to the Endodontic Department, Faculty of Dentistry, Institution University, diagnosed as asymptomatic irreversible pulpitis.
Clin Orthop Relat Res
September 2025
Department of Neurosurgery, Leiden University Medical Centre, Leiden, The Netherlands.
Background: Lumbar spinal stenosis (LSS) is common in adults with achondroplasia and predisposes individuals to neurogenic claudication. It remains unverified whether the severity of stenosis in patients with achondroplasia is associated with clinical outcomes. Similarly, the role of sagittal balance parameters in clinical outcomes has not been determined.
View Article and Find Full Text PDFEur J Orthop Surg Traumatol
September 2025
University of Leeds, Leeds, United Kingdom.
Introduction: This study aimed to evaluate the health perception of quality of life and function in patients with segmental bone defects (SBD) of the femur or tibia treated with the Induced Membrane Technique (IMT) and achieved bone healing and infection control.
Methods: This cross-sectional cohort study was conducted at a single referral center. Patients with infected SBD of the femur or tibia treated with IMT were included if they had at least 12 months of bone healing and no evidence of infection.
Chin J Integr Med
September 2025
Department of Pulmonary and Critical Care Medicine/Department of Integrated Traditional Chinese and Western Medicine for Pulmonary Diseases Part 1, National Center for Integrative Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital; National Center for Respiratory Medicine; Ins
Objective: To observe the clinical effect and safety of Lu'e Biyan Formula (LBF) combined with loratadine in the treatment of moderate to severe allergic rhinitis (AR) patients with Fei (Lung)-qi deficiency-coldness (FQDC) syndrome.
Methods: From September 2023 to December 2024, moderate to severe AR patients with FQDC syndrome were recruited from the Outpatient Department of Integrated Traditional Chinese and Western Medicine for Pulmonary Diseases Part 1, China-Japan Friendship Hospital. Participants were randomly assigned to a test group and a control group by using a random number table at a ratio of 1:1.
Drug Des Devel Ther
September 2025
Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People's Republic of China.
Purpose: This study aimed to compare the analgesic efficacy of liposomal bupivacaine with that of traditional ropivacaine in adductor canal blocks for patients undergoing knee arthroplasty.
Patients And Methods: A total of 119 consenting participants, who were scheduled for elective knee arthroplasty (including total knee replacement and unicompartmental knee replacement) under general anesthesia, were randomly assigned to either receive an ultrasound-guided adductor canal block with ropivacaine or liposomal bupivacaine. The primary endpoint of this study was the pain scores at 2, 24, 48, and 72 hours post-surgery.