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Fahr's syndrome is a rare neurological disorder that shows up as calcium deposits in the brain, affecting motor control and cognitive functions. In this case report, a 45-year-old woman with schizophrenia was diagnosed with Fahr's syndrome, which can be challenging to diagnose due to coexisting neurological comorbidity.
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http://dx.doi.org/10.1002/ccr3.70093 | DOI Listing |
Ann Med Surg (Lond)
July 2025
Voice of Doctors Research School, Dhaka, Bangladesh.
Introduction And Importance: Fahr's syndrome is a rare neurodegenerative disorder characterized by bilateral intracranial calcifications, primarily affecting the basal ganglia, thalamus, and cerebellum. It presents with a wide range of neurological and psychiatric symptoms, often mimicking more common conditions.
Case Presentation: We report the case of a 45-year-old South Asian male with no known comorbidities who presented with acute fever, altered consciousness, and generalized tonic-clonic seizures.
Case Rep Endocrinol
July 2025
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Fahr's syndrome is a rare neurodegenerative condition characterized by bilateral progressive calcification of the basal ganglia and other brain structures. Due to overlapping symptoms, it can be misdiagnosed as other neurological disorders. A 68-year-old man was presented to the emergency department with an exacerbating decline in the level of consciousness and dysarthria over a 20-day period.
View Article and Find Full Text PDFIndian J Surg Oncol
June 2025
Department of Radiology, Medical Faculty, Ataturk University, Erzurum, Turkey.
Fahr's disease is defined as the accumulation of bilateral idiopathic calcification in the basal ganglia, dentate nucleus, and centrum semiovale. The coexistence of Fahr's disease and intracranial tumors is extremely rare, with only five cases documented in the literature. This study aimed to present a rare case, discussing both similarities and differences with previously reported cases.
View Article and Find Full Text PDFAACE Endocrinol Diabetes
April 2025
Department of Internal Medicine, Germina Group, Universidad Industrial de Santander, Bucaramanga, Colombia.
Background/objective: Bilateral basal ganglia calcifications are rare manifestations of neurodegenerative disorders associated with disturbances of brain calcium-phosphorus homeostasis. This report describes a patient with Fahr's syndrome secondary to normocalcemic primary hyperparathyroidism, a rarely reported entity that should be considered as a differential diagnosis.
Case Report: A 61-year-old woman consulted the medical service stating: "I had a seizure and fell off my motorcycle.
Neurocase
August 2025
Department of Laboratory Medicine, Xi'an Mental Health Center, Xi'an, P.R. China.
Fahr's disease (FD) is a rare neurological disorder that causes abnormal, symmetrical, and bilateral calcification of the basal ganglia and other brain regions. Psychiatric symptoms are one of the many manifestations that guide FD diagnosis, with most usually occurring by ages 30-60 years. Herein, we report an incidental finding of bilateral basal ganglia calcification in a 14-year-old male teenager presenting psychotic characteristics, including schizophreniform and manic-like symptoms, who was initially investigated for mycoplasma infection.
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