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Background: Medial patellofemoral ligament reconstruction (MPFLR) is an excellent surgical option for patients with recurrent patellar instability. This technique has demonstrated significant improvements in patient-reported outcomes, high rates of return to sport, and low rates of failure. However, there is debate regarding the use of isolated MPFLR in the setting of concomitant pathoanatomic features such as patella alta, trochlear dysplasia, or a lateralized tibial tubercle.
Purpose: To estimate the overall relative effect sizes as well as strength of evidence supporting described risk factors for recurrent instability after isolated MPFLR.
Study Design: Systematic review and meta-analysis.
Methods: A systematic review was performed in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The PubMed, Embase, Cochrane, and Ovid/MEDLINE databases were queried. Clinical studies for outcomes of isolated MPFLR reporting recurrent instability and associated risk factors were included. Data for each risk factor analyzed by at least 2 studies were extracted, and the heterogeneity of studies was determined by value. For variables evaluated in studies determined to have fair homogeneity, defined as <25%, DerSimonian-Laird random-effects models were generated and effect sizes were represented as mean differences or odds ratios.
Results: Nine studies examining risk for recurrent instability after isolated MPFLR were identified, with 5 overlapping risk factors with low heterogeneity between studies: age, sex, tibial tubercle to trochlear groove (TT-TG) distance, Caton-Deschamps Index (CDI), and trochlear dysplasia. There was strong evidence to support the risk of recurrent instability associated with CDI >1.3 (OR, 2.72; = .02) and dysplasia with a trochlear bump (DeJour type B or D; OR, 3.28; <.001). Age, sex, and TT-TG distance did not cause an increased risk of recurrent instability with currently available aggregate data.
Conclusion: There are signs of increased risk of failure of isolated MPFLR in the setting of DeJour type B and D trochlear dysplasia and patella alta (CDI, >1.3). Currently available data suggest that age, sex, and TT-TG distance do not cause a higher risk of recurrence for patients undergoing isolated MPFLR.
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http://dx.doi.org/10.1177/03635465241266594 | DOI Listing |
Curr Sports Med Rep
September 2025
Department of Orthopaedics, University of North Carolina School of Medicine, Chapel Hill, NC.
Glenohumeral instability is a common injury affecting contact and collision athletes. Male sex, younger age at time of first dislocation, and contact sports participation are risk factors for recurrent instability. MRI is the gold standard to evaluate soft tissue structures, while CT is beneficial in quantifying glenoid bone loss and identifying on-track and off-track Hill-Sachs lesions.
View Article and Find Full Text PDFRev Cardiovasc Med
August 2025
Department of Cardiology, Affiliated Hospital of Hangzhou Normal University, Zhejiang Key Laboratory of Medical Epigenetics, School of Basic Medical Sciences, Hangzhou Institute of Cardiovascular Diseases, Engineering Research Center of Mobile Health Management System&Ministry of Education, Hangzhou
Background: Depression is a highly prevalent mental disorder worldwide and is often accompanied by various somatic symptoms. Clinical studies have suggested a close association between depression and cardiac electrophysiological instability, particularly sudden cardiac death (SCD) and arrhythmias. Therefore, this review systematically evaluated the association between depression and the risks of SCD, atrial fibrillation (AF), and ventricular arrhythmias.
View Article and Find Full Text PDFNeurol Res
September 2025
Henan Provincial People's Hospital, Department of Surgery of Spine and Spinal Cord, People's Hospital of Zhengzhou University, Zhengzhou, China.
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J Am Acad Orthop Surg
September 2025
From the Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY (Neitzke, O'Donnell, Buchalter, Chandi, Westrich, and Gausden), the Department of Orthopedic Surgery, University of Wisconsin-Madison, Madison, WI (O'Donnell), and Somers Orthopaedic Surgery & Sports Medicine Group
Introduction: Developmental dysplasia of the hip (DDH) poses challenges for component positioning during total hip arthroplasty (THA) secondary to abnormal bone morphology, soft-tissue contractures, and hip center migration. The objective of this study was to evaluate the radiographic and clinical outcomes of THA for DDH performed with robotic assistance versus manual (M) technique.
Methods: A retrospective review identified 115 patients with Crowe II to IV dysplasia undergoing primary THA at a single institution from 2016 to 2022.
JBJS Rev
September 2025
Department of Orthopaedic Surgery and Rehabilitation, Loyola University Medical Center, Maywood, Illinois.
» Posterior shoulder instability (PSI) constitutes approximately 10% of all shoulder instability cases and is prevalent among contact sport athletes because of recurrent blunt trauma to the shoulder.» PSI presents as persistent pain and can be diagnosed using clinical tests such as the Kim test and the Jerk test.» Surgical intervention is recommended for athletes who have exhausted nonoperative treatment.
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