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Background: Based on the presenting injury, patients undergoing abuse evaluation may be managed by different specialties. Our local child abuse specialist expressed concern over the variability in evaluation of patients presenting with injuries concerning for non-accidental trauma (NAT). The aim of this quality improvement project was to increase the percentage of patients for whom there is a concern for NAT who receive a guideline-adherent evaluation from 7.7% to 50% in 6 months' time.
Methods: A committee of physician stakeholders developed criteria for a complete NAT evaluation which were integrated into an order panel with built-in clinical guidance for test selection within our electronic medical record. Data on the completeness of NAT evaluation in paediatric patients 0-18 years of age were collected before and after the order panel release and analysed by admitting service, injury category and equity factors.
Results: This initiative increased the percentage of patients with a guideline-adherent evaluation from a mean of 7.7% to 25% within 6 months' time. The number of days between patients with complete evaluations decreased from 63 days to 35 days. Order panel utilisation increased to 55%, and the percentage of evaluation opportunities was more complete when the order panel was used (79% vs 92%).
Conclusions: Standardisation of NAT evaluations through creation of an order panel with a clinical decision tool resulted in more guideline-adherent evaluations. The potential reduction of bias in such evaluations remains an area of interest.
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http://dx.doi.org/10.1136/bmjoq-2024-002953 | DOI Listing |
Appl Environ Microbiol
September 2025
Department of Biology, University of Regina, Regina, Saskatchewan, Canada.
Unlabelled: Bovine respiratory disease (BRD) is the primary disease of cattle and is responsible for most of the antibiotic use in the beef industry, both for metaphylaxis and treatment. Infection prevention and targeted treatments would benefit from detecting and identifying bacterial pathogens and, ideally, assessing antibiotic sensitivity. Here, we report success refining targeted metagenomics by hybridization capture sequencing (CapSeq) to detect and genotype bacterial pathogens and genes for antibiotic resistance in BRD.
View Article and Find Full Text PDFActa Psychol (Amst)
September 2025
College of Hospitality and Tourism Management, Sejong University, 98 Gunja-Dong, Gwanjin-Gu, Seoul 143-747, Republic of Korea.
An industrial trend regarding a surging amount of attention to central bank digital money (CBDM) by government bodies and consumers has recently been observed. The aim of this study is to assess the roles of the antecedents and moderators, which include fear of missing out, confidence of CBDM in the digitalized era, and attachment to CBDM, in regards to predicting CBDM adoption within the framework of the theory of planned behavior and the five phases of the consumer adoption process in order to keep up to date with this rapidly changing industrial trend. Data sets from 515 respondents were collected for empirical analyses via an online panel survey in order to achieve the research objectives.
View Article and Find Full Text PDFBlood Transfus
August 2025
EFS BloodCenter of Brittany, HLA-HPA Laboratory, Rennes, France.
Background: Non-invasive fetal HPA typing is a valuable tool to identify the pregnancies at risk of fetal and neonatal alloimmune thrombocytopenia (FNAIT). Different approaches have been developed, mainly based on real-time PCR and droplet digital-PCR. Those methods have a limited ability to multiplex and require replicates due to the contamination risk.
View Article and Find Full Text PDFClin Chem
September 2025
Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Background: Direct measurement of low-density lipoprotein cholesterol (LDL-C) is widely used and recommended by professional society guidelines despite its potential limitations in patients with hypertriglyceridemia and low LDL-C. This study evaluated the performance of 3 direct LDL-C (LDL-CD) assays, 2 modern LDL-C calculation methods [LDL-C Martin (LDL-CM), LDL-C modified Sampson (LDL-CS)] and the conventional Friedewald (LDL-CF) method against the reference method, beta-quantification (LDL-CBQ).
Methods: A total of 181 remnant sera from patients with standard lipid panel orders or from patients with LDL-CBQ orders with triglycerides (TG) ≥ 400 mg/dL (4.
Ann Geriatr Med Res
September 2025
Geriatric Education and Research Institute, Singapore.
Objective: To ascertain the construct validity and reliability of a self-administered web-based assessment of intrinsic capacity (IC).
Design: Cross-sectional data analysis of a prospective cohort study.
Settings And Participants: We included data from 6,434 respondents (age, mean (SD): 65.