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http://dx.doi.org/10.1097/EJA.0000000000002104 | DOI Listing |
JACC Case Rep
September 2025
Cardiology Unit, Cardiovascular Department, Humanitas Gavazzeni, Bergamo, Italy.
Background: We present a multimodality imaging study of a rare case of postsurgical chronically evolved pseudoaneurysm with a possible rupture buffered by the huge thrombus.
Case Summary: A patient known for previous late presentation myocardial infarction complicated by shock and ventricular septal defect and treated with surgical repair and triple coronary artery bypass grafting, was directed to our hospital for severe mitral regurgitation. Computed tomography, cardiac magnetic resonance, and echocardiography, in a multimodality approach, revealed a huge postsurgical cardiac pseudoaneurysm, with an extensive thrombus and the native pericardium not perfectly distinguishable from pseudoaneurysm tissue or surgical patch.
Pharm Res
September 2025
Michael E. DeBakey Department of Surgery, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77030, USA.
Purpose: Postsurgical pain (PSP) is a common complication in surgical patients that can progress to chronic pain and opioid dependence. Current analgesics, including opioids and non-opioid agents, are limited by short durations of action and adverse effects. This study reports the development and evaluation of extended-release bupivacaine microparticles (BuMPs) designed to provide sustained local analgesia and improve post-surgical pain management.
View Article and Find Full Text PDFReg Anesth Pain Med
August 2025
The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Background/importance: Spinal cord stimulation (SCS) is an established therapy for chronic pain conditions when conventional treatments fail. However, global research implementation varies significantly due to patient demographics, healthcare infrastructure, and economic factors, creating disparities in access that directly impact patient care and public health outcomes.
Objective: To evaluate the global landscape of SCS research by analyzing patient demographics, geographic distribution, funding sources, and pain conditions treated across chronic pain populations aged 18 years and older, with primary focus on associations between geographic regions and patient age demographics.
Maedica (Bucur)
June 2025
Department of Internal Medicine, ULS Viseu Dão-Lafões, Viseu, Portugal.
Exocrine pancreatic insufficiency (EPI) arises from a deficiency in pancreatic enzymes, leading to malabsorption and varied symptoms such as gastrointestinal discomfort, weight loss and steatorrhea. Though EPI commonly follows chronic pancreatitis or pancreatic surgery, its delayed onset is rarely discussed. We report a unique case of EPI manifesting 29 years after pancreaticoduodenectomy.
View Article and Find Full Text PDFBr J Anaesth
August 2025
Department of Anaesthesia, South Health Campus, Calgary, AB, Canada. Electronic address: