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The Kenya long-term exclosure experiment (KLEE) was established in 1995 in semi-arid savanna rangeland to examine the separate and combined effects of livestock, wildlife and megaherbivores on their shared environment. The long-term nature of this experiment has allowed us to measure these effects and address questions of stability and resilience in the context of multiple drought-rainy cycles. Here we outline lessons learned over the last 29 years, and how these inform a fundamental tension in long-term studies: how to balance the need for question-driven research with the intangible conviction that long-term data will yield valuable findings. We highlight the value of (1) identifying experimental effects that take many years to manifest, (2) quantifying the effects of different years (including droughts) and (3) capturing the signatures of anthropogenic change. We also highlight the potential for long-term studies to create a collaborative community of scientists that brings new questions and motivates continued long-term study.
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http://dx.doi.org/10.1111/ele.14466 | DOI Listing |
Front Reprod Health
August 2025
Division of Epidemiology & Biostatistics, School of Public Health, University of Illinois Chicago, Chicago, IL, United States.
Introduction: Adolescent sexual and reproductive health in low- and middle-income countries is critical to address following the COVID-19 pandemic. Growing evidence of its' impact includes increased teenage pregnancies and higher rates of unsafe abortion. Our qualitative study sought to understand perspectives and behaviours around these escalations.
View Article and Find Full Text PDFWorld J Clin Pediatr
September 2025
School of Medicine, College of Health Sciences, Uzima University, Kisumu 2502 - 40100, Kisumu, Kenya.
Background: Phocomelia is a rare congenital disorder characterized by the absence or underdevelopment of the proximal limbs. Phocomelia can occur as a syndrome or a limb-specific deformity. While historically linked to thalidomide, non-thalidomide causes include genetic mutations, vascular disruptions, and teratogenic exposures.
View Article and Find Full Text PDFSci Rep
August 2025
Strathmore Institute of Mathematical Sciences, Strathmore University, Nairobi, Kenya.
Goodness of fit (GOF) test approaches for selecting probability distributions of climatic variables are pervasive in the statistical literature. However, a combined approach of multiple tests remains underutilized despite evidence supporting their improved precision. Increased erratic climatic conditions pose severe threats to economic stability, necessitating robust statistical methods for climate modeling.
View Article and Find Full Text PDFWorld J Clin Pediatr
September 2025
Department of Medicine, Maseno University, Kisumu 3275-40100, Kenya.
Background: Congenital scoliosis (CS) is a spinal deformity caused by defective segmentation and development of vertebrae during early embryogenesis. It occurs in 0.5%-1% in 1000 births and may rarely occur with congenital defects affecting the heart or genitourinary system.
View Article and Find Full Text PDFFood Funct
August 2025
Department of Biotechnology and Environmental Science, College of Agriculture and Life Sciences, Kangwon National University, Chuncheon, Gangwon-do 24341, Republic of Korea.
A long-term high-fat diet (HFD) intake causes obesity, disrupting the gut microbiota and body metabolite balance, and increasing the risk of Alzheimer's disease (AD). Fermented hempseed may restore microbiota balance, improve metabolism, and reduce neuroinflammation, potentially protecting against cognitive decline. This study investigates the protective effects and mechanisms of action of KCTC 15831BP-fermented hempseed (FHS) against AD-like symptoms induced by obesity in high-fat diet-fed mice.
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