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A 3-year-old boy presented with an unusual combination of indurated skin, sclerotic plaques with lichenification, and yellowish papules. Histopathology revealed diffuse dermal mucin deposits, and laboratory tests showed a positive throat culture for Group A streptococcus and elevated serum anti-streptolysin titers. An 10-day course of oral amoxicillin was associated with near-complete resolution of all dermatological findings within 4 months. This case represents a unique presentation of a self-resolving cutaneous mucinosis, likely associated with a streptococcal infection.
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http://dx.doi.org/10.1111/pde.15856 | DOI Listing |
Ann Med Surg (Lond)
June 2025
Al-Ahli Hospital, Hebron, Palestine.
Introduction: Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis primarily affecting medium-sized vessels. It has several clinical manifestations, including renal, gastrointestinal, cutaneous, neurologic, and general symptoms, but it is not associated with pulmonary manifestations. PAN mainly affects individuals aged 40-60 years, with a male predominance.
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March 2025
Dermatopathology, Sagis Diagnostics, Houston, USA.
Coccidioides is a dimorphic fungus that causes coccidioidomycosis, also known as San Joaquin Valley Fever. The fungus is endemic to the southwestern United States, northern Mexico, and Central and South America. Infection is typically acquired through inhalation of dust particles that causes pulmonary disease.
View Article and Find Full Text PDFExpert Rev Mol Med
March 2025
Department of Research, Sir Gangaram Hospital, New Delhi, India.
Leishmaniasis, classified as a neglected tropical disease, exerts its impact on millions globally. Its clinical spectrum encompasses diverse forms, from benign self-resolving skin lesions (cutaneous leishmaniasis) to life-threatening visceral infections (visceral leishmaniasis or kala-azar). This review aims to comprehensively explore the spectrum of the disease as an outcome of often-overlooked parasite variants.
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February 2025
Dermatology, Dell Medical School, University of Texas at Austin, Austin, USA.
Toxic epidermal necrolysis-like acute cutaneous lupus erythematosus (TEN-like ACLE) is an acute, life-threatening manifestation of ACLE. Histiocytic necrotizing lymphadenitis (HNL) is a rare disease of lymph nodes that presents with fever and lymphadenopathy and is generally self-resolving. We report a case of a 48-year-old female who presented to the emergency department (ED) with fever and arthralgias in the setting of 30 lbs weight loss over two months.
View Article and Find Full Text PDFAn Bras Dermatol
August 2025
Department of Pathology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Background: Cutaneous squamous cell carcinoma (cSCC) includes in situ cSCC (Bowen's disease [BD]) and invasive cSCC. By contrast, keratoacanthoma (KA) is a well-differentiated cSCC with self-resolving tendencies. Dermoscopy aids in monitoring vascular and keratin pattern changes to diagnose and track cSCC invasion.
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