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Objective: The primary research aim was to determine if the use of traditional or 3D printed prosthesis resulted in better functional outcome scores in hip arthroplasty.
Methods: A systematic review and meta-analysis was conducted utilizing the PRISMA 2020 guidelines. Six databases (PubMed, Embase, Scopus, WebOfScience, and Cochrane Library, Google Scholar) were searched yielding 1117 article titles and abstracts. Rayyan.ai was used to detect duplicates (n = 246) and for manual screening for inclusion and exclusion criteria. Included were controlled studies of any publication time that assessed Harris Hip Score (HHS) at baseline and twelve months. Six papers were sought for full text review of which three studies totaling 195 hips met final inclusion.
Results: Mean HHS in the control group went from 38.15 (± 6.02) at baseline to 80.30 (± 4.79) at twelve months follow-up, while the 3D group saw a change from 37.81 (± 5.84) to 90.60 (± 4.49). Significant and large improvements between time points were seen within the control group [p = .02, Cohen's d = 8.57 (1.48, 15.56)] and 3D group [p < 0.01, Cohen's d = 9.18 (3.50, 14.86)]. The HHS score of the 3D group improved by 10.64 points more than the HHS score of the control group, which is a statistically insignificant (p = 0.89) amount.
Conclusion: Group differences in pooled mean HHS scores at twelve months follow-up surpassed established minimum differences for clinical importance. High quality research should be further pursued to elucidate these findings.
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http://dx.doi.org/10.1007/s00402-024-05650-6 | DOI Listing |
Menopause
September 2025
Bayer Consumer Care, Basel, Switzerland.
Importance: Sleep disturbances are common during and after the menopause transition, with potential effects on morbidity and quality of life; however, they may be underdiagnosed and undertreated.
Objective: We carried out a systematic literature review to investigate the prevalence and impact of sleep disturbances associated with menopause on women's health-related quality of life across the stages of menopause.
Evidence Review: Searches were conducted in PubMed and Excerpta Medica Database to identify articles published between 2013 and 2023 containing evidence for the impact of sleep quality on health-related quality of life and the epidemiology of sleep disturbances in women in menopause.
PLoS One
September 2025
Neonatology, Yan'an Hospital Affiliated to Kunming Medical University, Kunming City, Yunnan Province, China.
Purpose: To determine the experience of medication multiple in elderly patients with multiple chronic condition by systematically reviewing, retrieving, and synthesizing data from qualitative studies.
Methods: Nine databases were systematically searched for relevant contributions from the time of construction until October 30, 2024. All qualitative studies in English and Chinese exploring the real-life experiences, feelings, etc, of medication multiple in elderly patients with multiple chronic condition were included.
Arterial thrombosis is a multifaceted process characterized by platelet aggregation and fibrin deposition, leading to the occlusion of blood vessels. It plays a central role in cardiovascular conditions such as myocardial infarction and ischemic stroke. Gaining insight into the mechanisms underlying arterial thrombosis is essential for developing effective treatments aimed at preventing thrombotic events and reducing associated health burdens.
View Article and Find Full Text PDFFolia Phoniatr Logop
September 2025
Introduction There is no definitive, comprehensive guide for diagnosing stuttering in multilingual speakers, and research suggests that monolingual-based diagnostic criteria may lead to misidentification in this population. This systematic review aimed to identify and consolidate conventional diagnostic guidelines for multilingual speakers and evaluate their validity in light of empirical evidence on stuttering and multilingualism. Method A systematic review was conducted using PubMed, Science Direct, SAGE, CINAHL, and Google Scholar using specific MESH terms (e.
View Article and Find Full Text PDFMicrob Genom
September 2025
School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia 5371, Australia.
causes otitis media and severe diseases including pneumonia, meningitis and bacteraemia. The rise of antimicrobial resistance (AMR) in , facilitated by mobile genetic elements (MGEs), complicates infection treatment. While pneumococcal conjugate vaccine (PCV) deployment has reduced disease burden, non-vaccine serotypes (NVTs) have increased and now cause invasive disease.
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