Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11789955 | PMC |
| http://dx.doi.org/10.4103/lungindia.lungindia_449_24 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Forty years of global research on WHO's four critical priority fungal pathogens: Advances and prospects.
J Infect Public Health
August 2025
Infection Control Center, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, China; National Clinical Research Center for Geriatric Disorders (XiangYa Hospital), Changsha, Hunan Province 410008, China; Superbugs and Multidrug Resistant Microbes Infection Control Research Ce
Background: On October 25, 2022, the World Health Organization (WHO) released its first Fungal Priority Pathogen List (FPPL), classifying Cryptococcus neoformans (C. neoformans), Candida auris (C. auris), Aspergillus fumigatus (A.
View Article and Find Full Text PDFA landscape review with novel criteria to evaluate microbial drivers for cancer: priorities for innovative research targeting excessive cancer mortality in sub-Saharan Africa.
Front Cell Infect Microbiol
September 2025
Infectious Diseases and Oncology Research Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
The escalating cancer burden in Sub-Saharan Africa (SSA), with projected doubling of incidence and mortality by 2040, necessitates innovative, cost-effective strategies for prevention, diagnosis, and treatment. While known infectious triggers like HPV, hepatitis viruses, and account for an estimated 28.7% of cancers in SSA, the full scope of microbially-mediated oncogenesis remains underexplored.
View Article and Find Full Text PDFAzole Antifungals Under Pressure: Therapeutic Challenges and Multifaceted Resistance Mechanisms.
Curr Med Chem
September 2025
Laboratório de Estudos Avançados de Microrganismos Emergentes e Resistentes (LEAMER), Departamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Góes, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
Fungal infections have increased markedly in both incidence and severity over recent decades, driven in part by the emergence of novel pathogenic species harboring sophisticated resistance mechanisms against commonly used antifungal agents. This alarming trend is especially pronounced with azoles, which remain widely used in clinical settings due to their broad-spectrum activity and favorable oral bioavailability. Azoles exert their antifungal effect by inhibiting lanosterol 14α-demethylase, a key enzyme in the ergosterol biosynthesis pathway, thereby compromising the integrity, fluidity, and functionality of the fungal cell membrane.
View Article and Find Full Text PDFRose Bengal Electromagnetic Activation with Green Light for Infection Reduction (REAGIR) Study: A randomized, double-masked, sham-controlled clinical trial of rose bengal photodynamic therapy.
Ophthalmology
September 2025
Francis I. Proctor Foundation, University of California San Francisco, USA; UCSF Department of Ophthalmology, University of California, San Francisco, USA; Byers Eye Institute, Stanford University, Palo Alto, USA. Electronic address:
Objective: To determine the effect of adjunctive rose-bengal photodynamic therapy (RB-PDT) in the treatment of fungal, Acanthamoeba, and smear/culture negative infectious keratitis.
Study Design: This international, randomized, double-masked, sham controlled clinical trial, randomizes patients with corneal ulcers in a 1:1 fashion to one of two treatment arms: 1) Topical antimicrobial plus sham RB-PDT or 2) Topical antimicrobial plus RB-PDT.
Main Outcome Measures: The primary outcome was best spectacle-corrected visual acuity (BSCVA) at 6 months.
The frequency distribution of Aspergillus section Nigri from clinical and environmental samples in Iran.
BMC Microbiol
September 2025
Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Background: Aspergillus section Nigri is widely distributed in decaying plant materials in our environment. Although most of these species are known for food spoilage and some have industrial applications, some of these species, including Aspergillus tubingensis, A. welwitschiae, and A.
View Article and Find Full Text PDF