98%
921
2 minutes
20
Introduction: Testing cognitive functions in Indians with low literacy and linguistic diversity is challenging. We describe the adaptation process of a comprehensive neurocognitive test battery to suit both literate and illiterate aging rural Indians.
Methods: Following the International Test Commission (ITC) guidelines for cross-cultural adaptation, we adapted the COGNITO battery. This involved translating instructions, linguistic elements, and stimuli of each test from the original English version with the help of bilingual experts. Five stimuli across eight subtests were adapted to maintain construct equivalence and cultural relevance.
Results: The Kannada version of COGNITO, a digitally administered tool, was feasible and effective measure for assessing cognitive functions in Kannada-speaking aging individuals from a rural Indian population.
Discussion: We emphasize the importance of maintaining semantic and theoretical construct equivalence with the source tool, and ensuring cultural and socioeconomic congruence for the cross-cultural adaptation of computerized cognitive batteries.
Highlights: Assessed cognitive functions in rural elderly with low literacy and high linguistic diversity.Followed International Test Commission (ITC) guidelines for cross-cultural adaptation to suit literate and illiterate aging rural Indians.Maintained semantic and theoretical construct equivalence with the source tool, ensuring cultural and socioeconomic congruence for cross-cultural adaptation of cognitive batteries.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659948 | PMC |
http://dx.doi.org/10.1002/dad2.70009 | DOI Listing |
JPEN J Parenter Enteral Nutr
September 2025
Center for Sarcopenia and Malnutrition Research, Kumamoto Rehabilitation Hospital, Kumamoto, Japan.
Background: Limited evidence exists regarding the cognitive and physical improvement effects of medium-chain triglyceride (MCT) intake in patients with stroke. This study aimed to investigate the association between MCT-enhanced rice consumption and enhancements in outcomes, including cognitive level, in patients following stroke.
Methods: We performed a retrospective cohort study on adults admitted to a rehabilitation center with cognitive decline following acute stroke.
Behav Res Methods
September 2025
Laboratoire de Psychologie, Université de Bordeaux, LabPsy UR 4139, 3 Place de la Victoire, 33076, Bordeaux Cedex, France.
This article presents a new set of semantic feature production norms, collected from 580 young adults, for 360 French concepts across various semantic categories. Although empirically derived feature norms have been developed for several languages and have been shown to be useful for investigating semantic memory and providing assessment tools, none are currently available for native French-speaking populations. In this study, the participants performed a property generation task in which they were asked to list features to describe the characteristics of each given concept (e.
View Article and Find Full Text PDFMol Psychiatry
September 2025
Center for Gene Regulation in Health and Disease, Cleveland State University, Cleveland, OH, 44115, USA.
Dysregulated spine morphology is a common feature in the pathology of many neurodevelopmental and neuropsychiatric disorders. Overabundant immature dendritic spines in the hippocampus are causally related to cognitive deficits of Fragile X syndrome (FXS), the most common form of heritable intellectual disability. Recent findings from us and others indicate autophagy plays important roles in synaptic stability and morphology, and autophagy is downregulated in FXS neurons.
View Article and Find Full Text PDFActa Pharmacol Sin
September 2025
Key Laboratory of Mental Health of the Ministry of Education, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Guangdong-Hong Kong Joint Laboratory for Psychiatric Disorders, Guangdong Province Key Laboratory of Psychiatric Disorders, Guangdong Bas
Recent investigations into the rapid antidepressant effects of ketamine, along with studies on schizophrenia-related susceptibility genes, have highlighted the GluN2A subunit as a critical regulator of both emotion and cognition. However, the specific impacts of acute pharmacological inhibition of GluN2A-containing NMDA receptors on brain microcircuits and the subsequent behavioral consequences remain poorly understood. In this study, we first examined the effects of MPX-004, a selective GluN2A NMDA receptor inhibitor, on behavior within the dorsomedial prefrontal cortex (dmPFC).
View Article and Find Full Text PDFSignal Transduct Target Ther
September 2025
Spine & Spinal Cord Institute, Department of Neurosurgery, College of Medicine, Yonsei University, Seoul, Republic of Korea.
Neuroregeneration and remyelination rarely occur in the adult mammalian brain and spinal cord following central nervous system (CNS) injury. The glial scar has been proposed as a major contributor to this failure in the regenerative process. However, its underlying molecular and cellular mechanisms remain unclear.
View Article and Find Full Text PDF