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Background This comparative study evaluates the performance of medical/surgical and mixed intensive care units (ICUs) at a tertiary care university hospital in Riyadh, Saudi Arabia, using key performance indicators (KPIs). Since its establishment in 1982, the hospital has provided comprehensive medical services, including specialized, closed-model ICUs, including medical, surgical, and pediatric ICUs. In 2021, these ICUs transitioned to a mixed ICU model to enhance efficiency and patient care. This study aims to assess the impact of this transition on various KPIs, including mortality rate, ICU length of stay (LOS), bed occupancy rate (bOR), ICU readmission rate within 48 hours, unplanned extubation, glycemic control, and delayed ICU discharge. Methodology Data from 2018 to 2022 were analyzed, comparing the separate medical and surgical ICUs model (2018-2020) with the mixed ICU model (2021-2022). Statistical analyses were performed, including independent t-tests and analysis of variance (ANOVA), to determine significant differences between the ICU models. Results The transition to the mixed ICU model significantly improved several KPIs. The standardized mortality ratio (SMR) decreased from 0.575 in the specialized ICU model to 0.399 in the mixed ICU model, reflecting a marked improvement in patient outcomes. The average LOS also reduced from 4.989 days in the specialized ICUs to 4.481 days in the mixed ICU model. Additionally, the bOR significantly dropped from 91.00% to 72.08% ( = 0.000), enhancing resource efficiency. Readmission rates within 48 hours were reduced from 0.883 to 0.475 and delayed ICU discharge rates also improved, falling from 34.59% to 23.31%. Our findings revealed that the mixed ICU model outperformed the specialized ICU in most KPIs, reflecting notable enhancements in operational efficiency and patient outcomes. Conclusions The transition to a mixed ICU model led to significant improvements in KPIs, including reductions in mortality rate and average LOS, alongside enhanced bOR and lower readmission rates within 48 hours. Delayed ICU discharge rates and glycemic control also showed notable positive changes. These improvements likely stem from the interdisciplinary expertise and flexibility of the mixed ICU environment, which supports better resource allocation and patient care. The study underscores the potential of mixed ICUs to optimize both clinical outcomes and operational efficiency in hospitals. Implementing such models can serve as a robust strategy for improving ICU performance. However, further research is needed to evaluate the long-term effects and assess the applicability of this model in diverse healthcare settings to fully validate its benefits.
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http://dx.doi.org/10.7759/cureus.74100 | DOI Listing |
Infect Drug Resist
September 2025
Department of Emergency, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, Zhejiang, 324000, People's Republic of China.
Introduction: Severe community-acquired pneumonia (SCAP) in immunocompromised patients is often caused by rare atypical pathogens, which are difficult to detect using conventional microbiological tests (CMTs) and can progress to sepsis in severe cases. Metagenomic next-generation sequencing (mNGS), an emerging pathogen detection technique, enables rapid identification of mixed infections and provides valuable guidance for clinical treatment decisions. SCAP-induced sepsis caused by a six-pathogen co-infection has not been previously reported, but interpretation remains a challenge.
View Article and Find Full Text PDFCrit Care Explor
September 2025
Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Professions, Gainesville, FL.
Objectives Background: Monocyte anisocytosis (monocyte distribution width [MDW]) has been previously validated to predict sepsis and outcome in patients presenting in the emergency department and mixed-population ICUs. Determining sepsis in a critically ill surgical/trauma population is often difficult due to concomitant inflammation and stress. We examined whether MDW could identify sepsis among patients admitted to a surgical/trauma ICU and predict clinical outcome.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Importance: Exposure to inflammation from chorioamnionitis places the fetus at higher risk of premature birth and may increase the risk of neurodevelopmental impairments, though the evidence for the latter is mixed.
Objective: To evaluate whether moderate to severe histologic chorioamnionitis (HCA) is directly associated with adverse motor performance, independent of the indirect mediating effects of premature birth.
Design, Setting, And Participants: This prospective, population-based cohort study recruited participants between September 16, 2016, and November 19, 2019, from referral and nonreferral neonatal intensive care units of 5 southwestern Ohio hospitals.
Aim: To explore the factors affecting the sustainable improvement of nurses' evidence-based practice (EBP) competency after receiving an EBP training program.
Design: A sequential mixed-methods study.
Methods: Thirty-seven ICU nurses participated from an adult ICU in Egypt.
Rev Esc Enferm USP
September 2025
Universidade de São Paulo, Escola de Enfermagem, Departamento de Enfermagem Médico-Cirúrgica, São Paulo, SP, Brazil.
Objective: To compare the performance of trauma severity indices (ISS, NISS, REMS, mREMS) in predicting hospital and Intensive Care Unit (ICU) admission outcomes.
Method: Retrospective cohort study carried out with patients treated at the Emergency Room of a private hospital from January 2020 to January 2022. Medical records of adults with blunt, penetrating, or mixed trauma admitted up to 24 hours after the trauma were analyzed.