Skeletal Stem Cells: A Basis for Orthopaedic Pathology and Tissue Repair.

J Bone Joint Surg Am

Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY.

Published: February 2025


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Article Abstract

➢ Skeletal stem cells (SSCs) continually replenish mature cell populations to support skeletal homeostasis.➢ SSCs repopulate by self-renewal, have multilineage potential, and are long-lived in vivo.➢ SSCs express specific combinations of cell surface markers that reflect their lineage identity.➢ SSCs adapt to their anatomic environment to support regional differences in skeletal behavior and pathology.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839314PMC
http://dx.doi.org/10.2106/JBJS.24.00905DOI Listing

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