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Objective: Describe surgical decision making and outcomes in a series of patients with persistent VPI after pharyngeal flap placement that were all treated with revision palatoplasty.
Design: Retrospective, case series.
Participants: Five patients with nonsyndromic cleft palate and persistent hypernasality following a pharyngeal flap. On MRI, 3 patients presented with an incohesive levator veli palatini muscle, and 4 patients had a pharyngeal flap that was below the palatal plane.
Interventions: One patient underwent straight-line intravelar veloplasty (IVVP), 2 patients underwent pharyngeal flap take-down and IVVP, and 2 patients underwent pharyngeal flap take-down and palate lengthening with buccal myomucosal flaps.
Main Outcome Measure: Pre- and postoperative resonance.
Results: Four of five patients (80%) achieved normal resonance 12 months postoperation.
Conclusions: Revision palatoplasty may be an effective approach for treating patients with persistent hypernasality following a pharyngeal flap. MRI may aid in surgical selection based on patient-specific anatomical findings.
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http://dx.doi.org/10.1177/10556656241307740 | DOI Listing |
Eur Arch Otorhinolaryngol
September 2025
Otorhinolaryngology and Skull Base Center, AP-HP, Hospital Lariboisière, Paris, 75010, France.
Purpose: Cocaine-induced midline destructive lesions (CIMDL) represent a rare but severe consequence of intranasal cocaine abuse, occasionally progressing to skull base involvement with life-threatening complications. The aim of this manuscript is to describe an exceptional case of CIMDL with clival destruction and brainstem exposure, and to review current management strategies based on a systematic literature review.
Methods: We report a unique case of a 39-year-old woman with CIMDL extending to the clivus, resulting in encephalocele with basilar artery and brainstem exposure.
Stomatologiia (Mosk)
September 2025
Central Research Institute of Dentistry and Maxillofacial Surgery, Moscow, Russia.
Objective: Improving the effectiveness of primary surgery of uranoplasty and re-reconstruction of the palate in patients with cleft palate through the use of an axial flap of the fat body of the cheek.
Material And Methods: In the period from 2023-2024, 41 patients with cleft palate aged from 1 to 19 years were operated on. Of these, 28 people had a flap of the cheek fat body used in risk groups during primary uranoplasty (group 1) and in 13 patients to eliminate postoperative palate defects of various localization and extent (group 2).
J Craniofac Surg
September 2025
Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Hwasun Hospital, Hwasun, South Korea.
The aim of this study was to evaluate the efficacy of endoluminal vacuum-assisted closure (EndoVAC) therapy for patients with pharyngocutaneous fistula by placing a sponge in the intraluminal pharyngeal space using a transoral approach. The authors retrospectively enrolled 12 patients with pharyngocutaneous fistula, who were treated with EndoVAC therapy from 2023 to 2024. Of the 12 patients, 10 patients had pharyngocutaneous fistula after surgery for head and neck malignancy, 1 patient had a leak in the pharyngoesophageal junction caused by bougienage, and 1 patient had a pharyngocutaneous fistula associated with antiphospholipid syndrome.
View Article and Find Full Text PDFZhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
August 2025
Department of Thyroid Head and Neck Ward 3, Liaoning Cancer Hospital &Institute, Shenyang 110042, China.
Am J Med Genet C Semin Med Genet
August 2025
School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Myhre syndrome is a rare connective tissue disorder characterized by skeletal, cardiopulmonary, dermatologic, neurocognitive changes, and a predisposition to exaggerated fibrosis in response to mechanical stress. We report monozygotic male twins with Myhre syndrome caused by the recurrent SMAD4 gain-of-function variant c.1498A>G (p.
View Article and Find Full Text PDF