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http://dx.doi.org/10.1161/CIRCIMAGING.124.017546 | DOI Listing |
Skeletal Radiol
September 2025
Department of Radiology, Hospital do Coração (HCor), Rua Desembargador Eliseu Guilherme, 53, 7th floor. CEP, São Paulo, SP, 04004-03, Brazil.
Atypical proximal tibial fractures in adolescents are rare, particularly when linked to hormonal therapy for short stature. This case series reports the clinical and imaging features of atypical proximal tibial and distal femoral physeal fractures in male adolescents undergoing combined growth hormone (GH) and aromatase inhibitor (AI) therapy for idiopathic short stature. We report three cases of skeletally immature male adolescents (ages 12-16) treated with GH and anastrozole who presented with acute leg pain following low-energy trauma during soccer.
View Article and Find Full Text PDFJACC Case Rep
September 2025
Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois, USA; Northwestern Feinberg School of Medicine, Chicago, Illinois, USA.
Background: Loeys-Dietz syndrome (LDS) is a rare connective tissue disorder (CTD) with musculoskeletal, craniofacial, and cardiovascular features with a prevalence of approximately 1:50,000. Morbidity and mortality often occur earlier in patients with LDS compared to patients with other CTDs.
Case Summary: We present a teenager with subacute heart failure, 4/6 holosystolic murmur with diastolic rumble, facial differences, and arachnodactyly.
Ned Tijdschr Geneeskd
September 2025
Reinier de Graaf Gasthuis, afd. Dermatologie, Delft.
This case report describes the presence of an acquirednaevus of Ito on a 78-year-old Dutch male. Naevus of Ito is a blue-grey discolouration that most commonly presents on Asian individuals during childhood. It is exceedingly rare for this naevus to occur later in life in a non-Asian individual.
View Article and Find Full Text PDFJ Pediatr Hematol Oncol
September 2025
Children's Hospital of Michigan, Division of Hematology/Oncology.
Glanzmann thrombasthenia (GT) is a rare autosomal recessive platelet disorder characterized by abnormalities in platelet aggregation, resulting from quantitative or qualitative defects in integrins αIIb and β3. Currently, allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only potentially curative therapeutic approach for severe GT. In this report, we present 2 children with GT that underwent successful allo-HSCT, along with 2008 to 2022 data from the Center for International Blood and Marrow Transplant Research and a summary of the existing literature providing further evidence that allo-HSCT can be a curative approach that prevents severe and life-threatening bleeding in GT.
View Article and Find Full Text PDFActa Derm Venereol
September 2025
CHU Lille, Urgences Pédiatriques & Maladies Infectieuses, Hôpital R. Salengro, Lille, France; University of Lille, URL2694: METRICS, Lille, France.
Some patients with slow-flow vascular malformations (SFVMs) develop recurring cellulitis. The main objective of this study was to describe SFVMs in children. Other objectives were to determine the frequency of cellulitis episodes, and the factors associated with the occurrence of cellulitis.
View Article and Find Full Text PDF