JACC Cardiovasc Imaging
July 2025
Background: Older adult patients have been underrepresented in the pivotal trials comparing an invasive versus conservative management for non-ST-segment-elevation myocardial infarction (NSTEMI).
Methods: We performed an electronic search of MEDLINE, Embase, and Cochrane databases through September 2024 for randomized controlled trials comparing invasive versus conservative management of NSTEMI in patients aged ≥70 years.
Results: The final analysis included 7 randomized controlled trials with 2997 patients.
Purpose Of Review: The purpose of this review is to highlight the increasing importance of cardiac magnetic resonance (CMR) imaging in diagnosing and managing cardiac amyloidosis, especially given the recent advancements in treatment options.
Recent Findings: This review emphasizes the crucial role of late gadolinium enhancement (LGE) with phase-sensitive inversion recovery (PSIR) techniques in both diagnosing and predicting patient outcomes in cardiac amyloidosis. The review also explores promising new techniques for diagnosing early-stage disease, such as native T1 mapping and ECV quantification.