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Background: Enteral and oral feeding are crucial for infants with a gestational age <32 weeks during hospitalization, with potential for improved outcomes through optimized feeding practices.
Purpose: To shorten the time to achieve full enteral and oral feeding volumes in infants with a gestational age <32 weeks.
Methods: This pre-post-intervention study focused on patients with a gestational age <32 weeks in Shenzhen City, 44 bed NICU. Quality improvement interventions included workflow enhancements, breastfeeding education, and oral motor strategies. Analysis of feeding times and hospital stays was conducted using SPSS software, alongside a provider survey to project feasibility.
Results: Statistical significant improvements were seen in full enteral feeding time for infants under 28 weeks gestation and full oral feeding time for those between 28 and 30 weeks. Length of stay did not show significant differences between period. Providers unanimously found the intervention feasible and acceptable.
Implications: Quality improvement interventions can expedite achievement of full feeding volumes in preterm infants, with potential for enhanced feeding outcomes.
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http://dx.doi.org/10.1097/JPN.0000000000000898 | DOI Listing |
Croat Med J
August 2025
Sara Sila, Department of Pediatrics, Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital Zagreb, Klaićeva 16, 10000 Zagreb, Croatia,
Aim: To assess the efficacy of a multidisciplinary tube-weaning program.
Methods: This retrospective cohort study enrolled children with feeding tube dependency who had not responded to standard tube-weaning interventions. All participants underwent a structured two-week multidisciplinary tube weaning delivered in a day-hospital setting at the Children's Hospital Zagreb in the period from August 2016 to February 2023.
Nutr Clin Pract
September 2025
Department of Pediatrics, Mercer University School of Medicine, Macon, Georgia, USA.
Background: The purpose of our study was to describe the time to full oral enteral feeding for extremely low birth weight (ELBW) infants in the neonatal intensive care unit (NICU).
Methods: We conducted a retrospective chart review of ELBW infants born at a regional medical center between July 1, 2021, and December 31, 2022. Infants who died or were transferred before discharge from the NICU were excluded from the study.
Transplant Cell Ther
September 2025
Division of Pharmacy, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Background: Pediatric patients undergoing hematopoietic stem cell transplant (HSCT) are at high risk for fungal infections including Candida, Aspergillus, and Mucorales necessitating the use of broad-spectrum antifungal agents such as posaconazole for prophylaxis and at times for treatment of invasive fungal infections. When first approved, posaconazole was limited to an immediate release oral suspension, which exhibited unreliable absorption dependent on co-administration with high fat meals. During HSCT, patients commonly have significant nausea, vomiting, and decreased enteral intake making this formulation particularly challenging.
View Article and Find Full Text PDFJ Oncol Pharm Pract
September 2025
Department of Otolaryngology, Bnei Zion Hospital, Haifa, Israel.
BackgroundMany oral medications are manufactured as solid dosage forms, posing challenges for patients with dysphagia-including older adults and children-and creating occupational hazards for healthcare workers who must crush or manipulate hazardous drugs. Existing methods for preparing such medications often involve open systems, exposing staff to cytotoxic agents and risking cross-contamination.ObjectiveTo develop and evaluate a novel, single-use closed-system drug-transfer device (CSTD) designed to crush and dissolve or suspend solid oral medications within a sealed environment, enhancing safety for healthcare workers and improving medication access for patients with swallowing difficulties.
View Article and Find Full Text PDFChin Clin Oncol
August 2025
School of Medicine, Valladolid University, Valladolid, Spain; Internal Medicine Unit, Río Hortega University Hospital, Valladolid, Spain.
Malnutrition and cachexia in cancer patients, particularly those with lung cancer, represent a pervasive clinical challenge that compromises treatment outcomes, quality of life, and overall survival. This article analyzes the multifactorial etiology of oncological malnutrition, highlighting the chronic inflammatory state, tumor-induced anorexia, and metabolic abnormalities that accelerate muscle and weight loss. It underscores that rates of malnutrition can range from 30% to 80% across different tumor types, with lung cancer patients especially vulnerable due to their high inflammatory burden.
View Article and Find Full Text PDF