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Depemokimab, the first ultra-long-acting anti-IL-5 monoclonal antibody for severe eosinophilic asthma. | LitMetric

Depemokimab, the first ultra-long-acting anti-IL-5 monoclonal antibody for severe eosinophilic asthma.

Med

Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy; Policlinico "G. Rodolico - San Marco" University Hospital, Catania, Italy. Electronic address:

Published: December 2024


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Article Abstract

Depemokimab, the first ultra-long-acting anti-IL-5 monoclonal antibody, significantly reduced exacerbation rates in patients with severe eosinophilic asthma when administered biannually. While it offers potential benefits for patient adherence and convenience, the trials showed no improvement in symptoms and lung function. Further research is needed to determine its optimal place in therapy and identify patients who will benefit the most.

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Source
http://dx.doi.org/10.1016/j.medj.2024.10.022DOI Listing

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