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In the field of biomedical science, blood cell detection in microscopic images is crucial for aiding physicians in diagnosing blood-related diseases and plays a pivotal role in advancing medicine toward more precise and efficient treatment directions. Addressing the time-consuming and error-prone issues of traditional manual detection methods, as well as the challenge existing blood cell detection technologies face in meeting both high accuracy and real-time requirements, this study proposes a lightweight blood cell detection model based on YOLOv8n, named GPMB-YOLO. This model utilizes advanced lightweight strategies and PGhostC2f design, effectively reducing model complexity and enhancing detection speed. The integration of the simple parameter-free attention mechanism (SimAM) significantly enhances the model's feature extraction ability. Furthermore, we have designed a multidimensional attention-enhanced bidirectional feature pyramid network structure, MCA-BiFPN, optimizing the effect of multi-scale feature fusion. And use genetic algorithms for hyperparameter optimization, further improving detection accuracy. Experimental results validate the effectiveness of the GPMB-YOLO model, which realized a 3.2% increase in mean Average Precision (mAP) compared to the baseline YOLOv8n model and a marked reduction in model complexity. Furthermore, we have developed a blood cell detection system and deployed the model for application. This study serves as a valuable reference for the efficient detection of blood cells in medical images.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632753 | PMC |
http://dx.doi.org/10.1007/s13755-024-00285-8 | DOI Listing |
JMIR Res Protoc
September 2025
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
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View Article and Find Full Text PDFChannels (Austin)
December 2025
Biorheology Research Laboratory, Faculty of Health, Griffith University, Gold Coast, Australia.
The hallmarks of mechanosensitive ion channels have been observed for half a century in various cell lines, although their mechanisms and molecular identities remained unknown until recently. Identification of the bona fide mammalian mechanosensory Piezo channels resulted in an explosion of research exploring the translation of mechanical cues into biochemical signals and dynamic cell morphology responses. One of the Piezo isoforms - Piezo1 - is integral in the erythrocyte (red blood cell; RBC) membrane.
View Article and Find Full Text PDFPol Merkur Lekarski
September 2025
Kharkiv Clinical Hospital on Railway Transport No. 1 ≪Health Care Center≫ of Joint-Stock Company «Ukrainian Railways», Kharkiv, Ukraine.
Objective: Aim: The purpose was to identify the morphological features of the great saphenous vein in patients with chronic venous disease of the lower extremities undergoing treatment with endovenous high-frequency electric welding in automatic mode, endovenous laser ablation, and ultrasound-guided microfoam sclerotherapy.
Patients And Methods: Materials and Methods: The material for the comprehensive morphological study consisted of fragments of the great saphenous vein obtained from 32 patients with chronic venous disease of the lower extremities. The material was divided into three groups according to the endovenous treatment techniques applied.
Pol Merkur Lekarski
September 2025
FACULTY OF NURSING, UNIVERSITY OF KUFA, KUFA, IRAQ.
Objective: Aim: To evaluate clinical applicability of immune mediator's interleukin-16, immunoglobulin E along with eosinophil count in diagnosing COVID-19 and determining its severity.
Patients And Methods: Materials and Methods: Cross-sectional case-control study was conducted at Al-Najaf General Hospital, Najaf, Iraq between March and August 2024. 120 participants: 60 confirmed COVID-19 cases and 60 healthy controls which matched cases in terms of age and sex.