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Social identity biases, particularly the tendency to favor one's own group (ingroup solidarity) and derogate other groups (outgroup hostility), are deeply rooted in human psychology and social behavior. However, it is unknown if such biases are also present in artificial intelligence systems. Here we show that large language models (LLMs) exhibit patterns of social identity bias, similarly to humans. By administering sentence completion prompts to 77 different LLMs (for instance, 'We are…'), we demonstrate that nearly all base models and some instruction-tuned and preference-tuned models display clear ingroup favoritism and outgroup derogation. These biases manifest both in controlled experimental settings and in naturalistic human-LLM conversations. However, we find that careful curation of training data and specialized fine-tuning can substantially reduce bias levels. These findings have important implications for developing more equitable artificial intelligence systems and highlight the urgent need to understand how human-LLM interactions might reinforce existing social biases.
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http://dx.doi.org/10.1038/s43588-024-00741-1 | DOI Listing |
Nat Protoc
September 2025
Pharmacomicrobiomics Research Center and College of Pharmacy, Hanyang University, Ansan, Republic of Korea.
Metabolism is a fundamental process that shapes the pharmacological and toxicological profiles of drugs, making metabolite identification and analysis critical in drug development and biological research. Global Natural Products Social Networking (GNPS) is a community-driven infrastructure for mass spectrometry data analysis, storage and knowledge dissemination. GNPS2 is an improved version of the platform offering higher processing speeds, improved data analysis tools and a more intuitive user interface.
View Article and Find Full Text PDFJ Neurosci
September 2025
Division of Molecular and Integrative Physiology, Department of Biomedical Sciences, Southern Illinois University School of Medicine, Carbondale, IL, 62903
Aggressive behavior can be acquired through observation, providing adaptive advantages but also posing significant social risks. In humans, individuals repeatedly exposed to aggression are more likely to engage in violent behavior later in life. Yet, the environmental factors and neural mechanisms underlying observationally acquired aggression remain unclear.
View Article and Find Full Text PDFBMJ Open
September 2025
Department of Mental Health Nursing, University of Ghana, Accra, Ghana
Objective: This study aimed to examine the contextual barriers that may hinder the implementation of multiple family group therapy (MFGT) in Ghana's Lower Manya Krobo District.
Design: An exploratory, descriptive, qualitative study employing focus group discussions and in-depth interviews.
Setting: Atua Government Hospital in the Lower Manya Krobo District.
BMJ Open
September 2025
Radiotherapy Department, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, England, UK.
Introduction: There are estimated to be 3.4 million patients in the UK living after a diagnosis of cancer. We know very little about their quality of life or healthcare usage.
View Article and Find Full Text PDFSemin Vasc Surg
September 2025
Division of Vascular and Endovascular Surgery, Weill Cornell Medicine, 525 E 68(th) Street, F-835, New York, NY 10003. Electronic address:
As the population ages, the rate of identification and repair of complex aortic pathology in patients of advanced age is rising. The older adult patient, defined here as 80 years or older, presents unique challenges for aortic repair due to medical comorbidities, declining functional status and independence, and anatomic changes. In this review, the evidence-based risk assessment and perioperative management are discussed, including the use of geriatric assessment tools, frailty indices, and emerging prehabilitation strategies.
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