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Background Venous thromboembolism (VTE) prophylaxis in hospitalized patients, particularly those undergoing abdominal surgery for cancer, is critical to reducing the incidence of deep vein thrombosis (DVT) and pulmonary embolism (PE). Despite increased awareness, ensuring appropriate VTE prophylaxis post-discharge remains challenging. The National Institute for Health and Care Excellence (NICE) guidelines recommend prolonged prophylaxis in specific cases, yet compliance on discharge often falls short. Method A retrospective audit was conducted on 60 patients admitted for elective abdominal cancer surgery in a District General Hospital (DGH) from January to December 2023. This assessed compliance with VTE prophylaxis guidelines, both during admission and post-discharge. Following the first audit cycle, educational interventions for junior doctors, posters in relevant departments, and reminders in electronic patient records were implemented to enhance compliance. A second audit cycle was conducted over four months with 30 patients to evaluate the effectiveness of these interventions. Results Initial results showed 100% compliance with VTE assessments and inpatient prophylaxis but only 49.1% compliance with full 28-day post-discharge prophylaxis. Around 24.5% of patients received no further prophylaxis after discharge, while 20.8% exceeded the recommended duration. After the intervention, compliance with recommended VTE prophylaxis improved significantly, with 81.25% of patients completing the prescribed course and only 14.8% receiving inpatient-only prophylaxis. The number of patients exceeding 28 days of prophylaxis decreased from 20.8% to 3.7%. Overall, non-compliance fell from 50.9% to 18.5%. Conclusion Simple, targeted interventions, including education and reminders within electronic records, led to significant improvements in VTE prophylaxis compliance post-abdominal cancer surgery. Continued adherence to these strategies, alongside system-embedded reminders, is expected to sustain these improvements and further reduce VTE-related morbidity and mortality.
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http://dx.doi.org/10.7759/cureus.73186 | DOI Listing |
Am J Med
September 2025
Russell H. Morgan Department of Radiology and Radiological Science; Department of Oncology; Department of Urology; Johns Hopkins University School of Medicine, Baltimore, MD, Johns Hopkins Health System, Baltimore, MD. Electronic address:
Prior authorization requirements by health insurance plans have become a barrier to healthcare delivery in the United States in terms of clinical efficiency, patient and provider experience. Surveyed physicians report associations with care delays, reduced clinical effectiveness and compromised patient outcomes. In this systematic review, we synthesized the published evidence regarding harmful effects of prior authorization on disease management and patient outcomes.
View Article and Find Full Text PDFClin Appl Thromb Hemost
September 2025
The Maldives National University, Rahdhebai Hingun, Malé.
BackgroundCancer patients are at significantly increased risk of venous thromboembolism (VTE), a leading cause of morbidity and mortality in this population. While traditional anticoagulants like low-molecular-weight heparin (LMWH) and vitamin K antagonists (VKAs) are commonly used, their limitations have prompted growing interest in direct oral anticoagulants (DOACs), particularly Factor Xa inhibitors. However, concerns about bleeding risks persist.
View Article and Find Full Text PDFAppl Clin Inform
August 2025
Information Technology Services, UW Medicine, Seattle, Washington, United States.
Chemoprophylaxis reduces the risk of hospital-acquired venous thromboembolism (VTE), but is not reliably ordered. Our institution created a clinical decision support (CDS) interruptive alert to remind clinicians to order VTE chemoprophylaxis when it is missing for qualifying inpatients. Unfortunately, this alert has required repeated modifications to ensure accurate logic, and continues to generate negative feedback from users.
View Article and Find Full Text PDFInt J Clin Pharm
September 2025
Department of Pharmacy, The Third Affiliated Hospital of Chongqing Medical University, 1 Shuanghu Branch Rd, Yubei District, Chongqing, 401120, People's Republic of China.
Introduction: Venous thromboembolism (VTE) is a common and preventable complication in orthopedic surgery, yet adherence to prophylaxis guidelines remains suboptimal. A pharmacist-led anticoagulation care model based on the Pharmacist Early Active Consultation (PEAC) framework may enhance the quality and safety of VTE prevention in surgical patients.
Aim: This study aimed to evaluate the impact of a pharmacist-led Venous Thromboembolism Clinical Pharmaceutical Care (VTE-CPC) model, derived from the PEAC framework, on VTE prevention and anticoagulation quality in orthopedic surgery patients.
Thromb Res
August 2025
School of Medicine, University of California Riverside, Riverside, CA, United States of America; Department of Orthopaedics, Arrowhead Regional Medical Center, Colton, CA, United States of America. Electronic address:
Background: Venous thromboembolism (VTE) is a considerable source of morbidity, mortality, and economic burden within orthopaedic surgery. Our study aimed to analyze the characteristics and reasons for lawsuits pertaining to VTE levied against orthopaedic surgeons.
Methods: The Westlaw database was queried for cases filed between 1980 and 2023 against orthopaedic surgeons involving VTE, using the search terms "orthopaedic", "blood clot," "deep vein thrombosis," "venous thromboembolism," and "pulmonary embolism.