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Background: Misinformation represents a serious and growing concern for public health and healthcare health; and has attracted much interest from researchers, media, and the public over recent years. Despite increased concern about the impacts of misinformation on health and wellbeing, however, the concept of health misinformation remains underdeveloped. In particular, there is a need to clarify how certain types of health information come to be designated as "misinformation," what characteristics are associated with this classification, and how the concept of misinformation is applied in health contexts.
Aim: Developing a shared understanding of what it means for health information to be "misinformation" is an important first step to accurately identifying at-risk groups, clarifying pathways of vulnerability, and agreeing goals for intervention. It will also help to ensure that misinformation interventions are accessible, acceptable, and of benefit to the populations to which they are directed. We will therefore examine the characteristics, measurement, and applications of misinformation in health contexts.
Methods: We will undertake a hybrid concept analysis, following a framework from Schwartz-Barcott & Kim (2000). This framework comprises three phases: a theoretical phase, fieldwork phase, and final analysis phase. In the theoretical phase, a search of seven electronic citation databases (PsycInfo, socINDEX, JSTOR, CINAHL, Scopus, MEDLINE and PubMed Central via PubMed, and ScienceDirect) will be conducted in order to identify original research, review, and theoretical papers, published in English between 2016 and 2022, which examine "health misinformation." Data from the literature will be synthesised using evolutionary concept analysis methods from Rodgers (2000). In the fieldwork phase, a purposive sampling strategy will be employed to recruit stakeholders for participation in semi-structured interviews. Interviews will be analysed using thematic analysis. The final phase will integrate findings from the theoretical and fieldwork analyses.
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http://dx.doi.org/10.12688/hrbopenres.13641.2 | DOI Listing |
Qual Life Res
September 2025
The Kids Research Institute Australia, The University of Western Australia, P.O. Box 855, West Perth, WA, 6872, Australia.
Purpose: CDKL5 deficiency disorder (CDD) is a rare developmental and epileptic encephalopathy. Greater understanding of the smallest meaningful improvements for individuals with CDD in clinical trials and practice is needed for a person-centred approach to treatment efficacy. This study explored how parent/caregivers of people with CDD understood meaningful improvements and described change for priority functional domains including communication, gross motor, fine motor, feeding.
View Article and Find Full Text PDFPatient
September 2025
PPD Evidera Patient-Centered Research, Thermo Fisher Scientific, Waltham, MA, USA.
Background: Migraine care is often suboptimal owing to undertreatment, variation in clinical outcomes and administration methods among existing treatments, and between- and within-individual heterogeneity in the clinical course of migraine. In response to these challenges, preference studies have been increasingly conducted to inform treatment decision-making and development. However, gaps remain in understanding how treatment preferences have been assessed across different migraine studies.
View Article and Find Full Text PDFJ Behav Med
September 2025
Department of Psychology, University of Wisconsin-La Crosse, La Crosse, WI, USA.
Latent profile analysis (LPA) is in the finite mixture model analysis family and identifies subgroups by participants' responses to continuous variables (i.e., indicators); participants' probable membership in each subgroup is based on the similarity between the subgroup's prototypical responses and the person's unique responses.
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
September 2025
College of Information Science and Technology, Donghua University, Shanghai, China.
High cost of clinical trials hinders further enhancement of comprehensive mechanical properties of bioresorbable scaffolds (BRS). Therefore, a multi-objective optimization method combining surrogate modeling and finite element simulation is proposed, based on the evaluation of stents with various auxetic structures and materials. The results demonstrated that re-entrant hexagon stent made of PLA (PLA-RH stent) was a more ideal candidate, with superior radial recoil and force.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
Department Chemie- und Bioingenieurwesen, Lehrstuhl für Chemische Reaktionstechnik (CRT), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Egerlandstr. 3, 91058, Erlangen, Germany.
The supported catalytically active liquid metal solution (SCALMS) concept is based on catalytically active metals dissolved in a low-melting-point liquid metal matrix. These solid alloy particles, deposited over a high area support, transform into a liquid alloy under reaction conditions. In this work, GaPt SCALMS materials of varying composition are investigated and focus on the change in the alloy composition during preheating, the actual high temperature propane dehydrogenation at 823 K, and after cool-down.
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