Quantifying EDC Emissions from Consumer Products: A Novel Rapid Method and Its Application for Systematic Evaluation of Health Impacts.

Endocrine-disrupting chemicals (EDCs) are widely used in consumer products and have been associated with adverse public health outcomes and significant economic costs. We developed a rapid chamber method for measuring EDC emissions from consumer products, significantly reducing the time to reach steady state from weeks or months to minutes or hours. Using this method, we quantified EDC emissions from a wide range of products, determined the emission-control parameters, and established their relationship with the EDC content () and physicochemical properties. By incorporating data from consumer product databases and applying stochastic models, we systematically estimated emissions for 400 EDC-product combinations and assessed the associated exposure and disease burden for the U.S. population. Our results suggest that more than 60% of these combinations could result in carcinogenic disability-adjusted life years (DALYs) above the acceptable threshold. The overall disease burden caused by EDCs in consumer products can be substantial, with DALYs exceeding those associated with other pollutants, such as particulate matter, in a worst-case scenario. This study provides a valuable tool for prioritizing hazardous EDCs in consumer products, evaluating safer alternatives, and formulating effective intervention strategies, thereby supporting policymakers and manufacturers in making informed, sustainable decisions.