98%
921
2 minutes
20
Eyelid dermatitis is a common dermatologic concern representing a broad range of inflammatory dermatoses. The most commonly reported cause of eyelid dermatitis is allergic contact dermatitis (ACD), a type IV delayed hypersensitivity reaction caused by exposure to external allergens that is diagnosed via epicutaneous patch testing. The most common contact allergens associated with eyelid dermatitis are metals, fragrances, preservatives, acrylates, and topical medications, which may be found in a variety of sources, including cosmetics, ophthalmic medications, nail lacquers, and jewelry. Management involves strict allergen avoidance with an emphasis on patient counseling. In this review, we discuss the clinical manifestation, evaluation, patch test considerations, and management of eyelid ACD to provide a valuable reference tool in the management of patients presenting with eyelid dermatitis.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.12788/cutis.1113 | DOI Listing |
Front Allergy
August 2025
Independent Research Pharmacist, Cardiff, United Kingdom.
eyelash mites are increasingly associated with eye and skin inflammation in humans, and cause demodectic mange in mammals. Informal accounts of symptom improvement and reduced need for anti-allergy medicines, when reproduction is prevented, indicate a further role linking to rhinitis, asthma and dermatitis. Their mobility, allergenic debris and consequential immunological impact may also explain progression of allergies in the .
View Article and Find Full Text PDFInt J Mol Sci
August 2025
Dr. Phillip Frost Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL 33125, USA.
Interleukin (IL)-15 is primarily known as a pro-inflammatory and anti-apoptotic cytokine, which stimulates the proliferation and survival of key immunocytes, including macrophages (MACs). Yet, it remains unclear how IL-15 specifically impacts MACs in intact human skin, particularly immunoinhibitory, IL-10-producing/secreting M2 MACs (CD206IL-10). In the current pilot study, we explored this in organ-cultured healthy human eyelid skin in the presence of IFNγ (100 IU/mL) to mimic a pro-inflammatory signaling milieu found in several chronic immunodermatoses.
View Article and Find Full Text PDFContact Dermatitis
August 2025
Department of Occupational and Environmental Dermatology, Faculty of Medicine, Skåne University Hospital, Lund University, Malmö, Sweden.
Vet Ophthalmol
August 2025
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.
Objective: To evaluate the antimicrobial effect of 275 nm wavelength ultraviolet C (UV-C) light on the periocular area of canine eyes for preoperative disinfection compared to standard 10% povidone-iodine (PI) solution preparation.
Methods: The upper and lower eyelids of six research-bred beagles were equally divided into two sections (medial and lateral). Each section received periocular cleansing with one of the following treatments: (1) saline, (2) baby shampoo, (3) baby shampoo and PI solution, or (4) baby shampoo and UV-C light therapy.
J Dermatolog Treat
December 2025
Clinical Department of Dermatology, Medical University of Silesia, Zabrze, Poland.
Background: Dupilumab has revolutionized treatment of moderate-to-severe atopic dermatitis (AD). However, its use has been associated with ophthalmologic adverse events referred to as dupilumab-associated ocular surface disease (DAOSD), reported in up to 30% of patients. Although several risk factors have been proposed, the role of Demodex folliculorum remains poorly defined.
View Article and Find Full Text PDF