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Background: Cervical fixation is a common treatment for conditions like vertebral fractures, osteosarcoma, osteomyelitis, arthritis, and congenital disorders. The study was designed to assess the occurrence of high-riding vertebral artery (HRVA), narrow C2 pedicles (NC2P) and ponticulus posticus (PP), which pose risks of injuring vertebral artery (VA) during screw placement in cervical fixation procedures.
Methods: The study examined the prevalence of HRVA, NC2P and PP in 382 pedicle sides of the C2 vertebra using computed tomographic angiography scans. Specific measurements were taken, including the internal height (C2InH), and isthmus height (C2IsH) of C2, as well as NC2P width.
Results: HRVA was identified by specific measurements: C2IsH of ≤ 5 mm and/or C2InHof ≤ 2 mm. NC2P was defined as NC2P width ≤ 4 mm. The reliability between observers and within the same observer, along with the consistency across different software, was assessed. At least one HRVA was found in 9.6% of patients and at least one NC2P in 13% of patients. Females demonstrated higher rates of HRVA and NC2Ps on the left side, with right-side figures at 10.5% and 11.7% for HRVA and NC2Ps respectively, and left side figures at 14.1% for both. Males exhibited a reserve pattern, with higher rates on the right side, marked by 10.3% HRVA and 15% NC2Ps, compared to 5.6% and 11.3% on the left. Furthermore, males showed a significantly higher occurrence of NC2Ps over HRVA on both sides. The presence of PP with NC2Ps detected in 44% of cases, and with HRVA in 16% of cases, a difference found to be statistically significant.
Conclusions: The digital models incorporating HRVA, NC2P, and PP facilitated a comprehensive analysis of the VA pattern, assessment of the virtual screw trajectory line for VA pedicles, and the designation of specific regions during the procedure, ensuring increased safety planning instrumentation.
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http://dx.doi.org/10.1007/s00276-024-03526-3 | DOI Listing |
J Neurosurg Case Lessons
September 2025
Department of Neurosurgery, Hospital East-Limburg, Genk, Limburg, Belgium.
Background: Calcium pyrophosphate dihydrate (CPPD) deposition disease at the craniocervical junction (CCJ) typically presents with a retro-odontoid pseudotumor. Here, the authors report a case of CPPD-induced basilar impression, causing vertebral artery (VA) dissection and hemorrhage.
Observations: A 65-year-old male presented with worsening chronic cervicalgia, occipital headaches, and unstable tandem gait.
World Neurosurg
September 2025
Department of Anaesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. Electronic address:
Objective: The present study intends to conduct a comprehensive bibliometric analysis of the research pertaining to the treatment of vertebral artery stenosis, with the objective of elucidating the evolution and trends in therapeutic strategies.
Methods: A bibliometric analysis of publications spanning between January 1, 1980, and August 13, 2024, was conducted utilizing the Web of Science Core Collection database. The analysis and visualization of the data were performed using VOSviewer, CiteSpace, and R package "bibliometrix" software.
Ann Anat
September 2025
Department of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Greece; "VARIANTIS" Research Laboratory, Department of Clinical Anatomy, Mazovian Academy in Plock, Poland.
Background: The vertebral artery (VA) undergoes a critical anatomical transition as it pierces the dura mater at the craniocervical junction. Precise knowledge of dural penetration patterns and angulation is essential for diagnostic imaging, neurosurgical planning, and minimizing iatrogenic risk in posterior fossa procedures.
Methods: This retrospective imaging study evaluated 100 adult patients who underwent 1.
Eur J Orthop Surg Traumatol
September 2025
Human Anatomy Teaching and Research Section, School of Basic Medicine, Inner Mongolia Medical University, Hohhot, China.
Objective: Reveal the changing rule of the positional relationship between the uncinate process of cervical spine and vertebral artery by measuring the relevant parameters between the uncinate process of cervical spine and vertebral artery in different age groups.
Methods: A retrospective study was conducted on 1240 cases of cervical spine imaging data from 2018 to 2021 in the Radiology Department of the Affiliated Hospital of Inner Mongolia Medical University. The distance between the uncinate process superior ridge and vertebral artery and the maximum of pedicle transverse angle, the minimum of pedicle transverse angle, the range of pedicle transverse angle and the pedicle width were measured according to age groups.
Forensic Sci Int
August 2025
Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada.
We report the forensic and clinicopathological spectrum of 14 postmortem cases involving the vertebral artery. In all cases, there was either pontocerebellar infarction (n = 8) or subarachnoid hemorrhage (n = 6). The underlying pathology of the vertebral artery was segmental mediolytic arteriopathy (n = 5), traumatic rupture of the arterial wall (n = 3), arterial dissection (n = 2), or atherosclerosis (n = 4).
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