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This study aimed to analyze the results of auditory and vestibular function tests in patients with unilateral vestibular schwannoma and explore their association with tumor size. Clinical data from 81 patients diagnosed with unilateral vestibular schwannoma who underwent pure-tone audiometry(PTA), cervical and ocular vestibular evoked myogenic potentials(c/oVEMP), as well as video head impulse test(vHIT), and subsequently underwent surgical treatment, were retrospectively analyzed. Patients were categorized into groups based on tumor size: small (≤ 15 mm), medium(16-30 mm), and large (>30 mm), determined by the maximum tumor diameter on contrast-enhanced MRI scans. PTA results indicated hearing loss in 73 cases(90.1%); vestibular function tests revealed abnormal rates for the anterior semicircular canal, horizontal semicircular canal, posterior semicircular canal, utricle, and saccule at 29.6%, 77.8%, 54.3%, 90.1%, and 92.6%, respectively. Statistically, no significant differences were found in preoperative hearing test results among patients in different groups(=0.393, =0.676). However, significant differences were observed in horizontal semicircular canal gain(=-0.248, =0.025), abnormal rates of horizontal semicircular canal catch-up saccades(=0.507, <0.001), as well as cVEMP(χ²=15.111, =0.004) and oVEMP thresholds(χ²=18.948, <0.001) across varying tumor size groups. The extent of hearing loss in patients with vestibular schwannoma is not correlated with tumor size, whereas the degree of vestibular dysfunction demonstrates a correlation with tumor size.
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http://dx.doi.org/10.13201/j.issn.2096-7993.2024.12.005 | DOI Listing |
Front Neurol
August 2025
Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Introduction: External continuous perturbations using a motion platform have been developed by employing either sum-of-sines (SoS) or a pseudorandom ternary sequence (PRTS) of numbers to quantify body sway evoked in the medial-lateral (ML) or anterior-posterior (AP) directions, which ultimately helps understand the human postural control system. These stimuli have been provided via pitch tilts of the motion platform for evaluations of AP balance responses or roll tilts for ML balance responses. However, little is known about whether a healthy postural control system responds to 2-dimensional (2D) perturbations similarly when the perturbation stimuli are provided in semicircular canal coordinates (i.
View Article and Find Full Text PDFPhysiother Theory Pract
September 2025
Clinical Vestibulology Observer, Otoneurology Centre, Udaipur, India.
Background: Multi-canal benign paroxysmal positional vertigo (MC-BPPV) is a rare form of BPPV characterized by the simultaneous involvement of multiple semicircular canals, often resulting in complex diagnostic and therapeutic challenges. While MC-BPPV most commonly affects the posterior and horizontal semicircular canals, tri-canal involvement - especially with bilateral asymmetry - is exceedingly rare.
Purpose: To describe a unique case of tri-canal BPPV involving right posterior and horizontal semicircular cupulolithiasis and left horizontal semicircular canalolithiasis, successfully managed with a structured, sequential protocol of repositioning maneuvers including a novel Bascule maneuver.
Neurol Med Chir (Tokyo)
September 2025
Department of Neurosurgery, Keio University School of Medicine.
Skull base surgery requires precise spatial recognition; however, existing educational tools remain limited. To address this issue, we developed a step-by-step stereotactic three-dimensional anatomical model of the anterior transpetrosal approach using digital photogrammetry. Cadaveric dissection was subsequently performed in 17 steps, of which 10 were reconstructed into three-dimensional models.
View Article and Find Full Text PDFOtol Neurotol
August 2025
University of the Philippines Manila College of Medicine, Metro Manila, Philippines.
Objective: This study aims to report the clinical characteristics of patients with superior semicircular canal dehiscence and near-dehiscence and to evaluate the outcomes of repair using a novel technique: middle cranial fossa minicraniotomy with combined plugging and resurfacing using a bone plate enveloped in fascia.
Study Design: Retrospective case series.
Setting: Tertiary hospital in the Philippines.
Acta Otolaryngol
August 2025
Department of Audiology, Faculty of Health Sciences, Inonu University, Malatya, Turkey.
Background: The vestibular system is crucial for balance and gaze stability. Proprioceptive inputs from the musculoskeletal system significantly contribute to vestibular processing, especially under postural challenge.
Objectives: To examine how proprioceptive inputs in various body positions affect the vestibulo-ocular reflex (VOR) and otolith organ function.