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Developing a non-toxic, cost-effective, and user-friendly indicator for detecting milk freshness and spoilage, with potential applications in smart packaging, presents a significant challenge. In this study, we extracted natural anthocyanins (ACNs) from Jaman (Syzgium cumini) and incorporated it in to filter paper. The presence of ACNs in the extract was confirmed through UPLC-MS/MS analysis. To enhance stability and prevent leaching, the ACNs-loaded filter paper was coated with 1 % chitosan (CH). The sensor strips were thoroughly characterized using FTIR, contact angle measurements, XRD, and FE-SEM. These strips displayed a distinct and quantifiable color change from red to colorless to yellow across different pH levels. Additionally, in real-time milk spoilage detection, the sensor transitioned from light purple to colorless. The strips demonstrated reproducibility and stability, even under high temperatures and extreme pH conditions. These findings suggest that the ACNs-loaded sensor strips hold promise for use as smart packaging materials.
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http://dx.doi.org/10.1016/j.foodchem.2024.142181 | DOI Listing |
Cell Tissue Res
September 2025
Grupo de Investigaciones Biológicas y Moleculares (GIByM), Instituto de Química Básica y Aplicada del Nordeste Argentino (IQUIBA NEA), Universidad Nacional del Nordeste (UNNE)-CONICET, Corrientes, Argentina.
Angiogenesis, the formation of new blood vessels from pre-existing vasculature, is a crucial process in both physiological and pathological contexts, including cancer. Phospholipases A (PLAs), enzymes found in snake venoms, have attracted attention due to their potential antiangiogenic properties. In this study, we explored the antiangiogenic effects of PLA isoforms isolated from Bothrops diporus venom using a combination of in vivo and ex vivo models.
View Article and Find Full Text PDFMicrobiol Spectr
September 2025
United States Department of Agriculture, Agricultural Research Service (USDA-ARS), Southeast Poultry Research Laboratories, US National Poultry Research Center, Athens, Georgia, USA.
Infectious bursal disease (IBD), a highly contagious viral disease in young chickens, poses significant economic losses due to high mortality and immunosuppression. While IBD virus (IBDV) virulence is influenced by multiple genes, whole-genome sequencing (WGS) of IBDV is crucial for defining the strain pathotype and clinical profile. Flinders Technology Associates (FTA) cards are convenient for field sample collection, but their filter paper matrix can hinder nucleic acid recovery, impacting sequencing efficiency.
View Article and Find Full Text PDFISA Trans
August 2025
Department of Vehicle Engineering and Jiangsu Engineering Research Center of Vehicle Distributed Drive and Intelligent Wire Control Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China; Department of Vehicle Engineering and Jiangsu Engineering Research Center of Vehi
The steer-by-wire (SbW) system, as the core component of vehicle steering, needs to track the front wheel angle accurately. To mitigate the angle tracking accuracy degradation caused by D-Q axes coupling, time-varying motor electrical parameters, and load disturbance, a fractional-order adaptive fuzzy decentralized tracking control (FAFDTC) strategy is proposed in this paper. First, considering time-varying motor parameters, D-Q axes coupling, and fractional-order characteristics of components, a fractional-order SbW interconnected system is constructed to enhance its ability to characterize nonlinearities, time-varying dynamics, and system coupling.
View Article and Find Full Text PDFMar Environ Res
September 2025
College of Oceanography and Ecological Science, Shanghai Ocean University, Shanghai, 201306, China. Electronic address:
This review examines the chemical and ecological interactions between filter-feeding mussels and the green macroalga Ulva prolifera in integrated multi-trophic aquaculture (IMTA) systems. Mussels are crucial for nutrient recycling, as they filter water and release bioavailable compounds such as ammonium (NH), urea (CO(NH)), and dissolved organic matter (DOM). These compounds promote Ulva growth and enhance microbial activity.
View Article and Find Full Text PDFInt J Med Inform
September 2025
Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:
Background: Identifying patient-specific barriers to statin therapy, such as intolerance or deferral, from clinical notes is a major challenge for improving cardiovascular care. Automating this process could enable targeted interventions and improve clinical decision support (CDS).
Objective: To develop and evaluate a novel hybrid artificial intelligence (AI) framework for accurately and efficiently extracting information on statin therapy barriers from large volumes of clinical notes.