98%
921
2 minutes
20
Atypical bacterial pathogens present the ability to induce pulmonary damage. At present, there are no available phenotypic diagnosis tests that achieve up to 100% reliability. Therefore, clinicians must utilise molecular techniques for the detection and identification of these pathogens. The main objective of this research was to evaluate the prevalence of atypical bacteria in paediatric patients from different age groups. A total of 609 clinical samples were collected from paediatric patients who presented with an adverse respiratory condition during the period from March 2021 to February 2024. DNA was extracted from the samples, and end-point PCR was performed to detect atypical bacteria. Statistical analyses were performed to evaluate the bacterial prevalence and assess clinical data from newborns and mothers that could be related to RDS. A total of 139 patients exhibited at least one atypical organism (22.82%). was more prevalent in neonates, while and were more prevalent in older infants. Atypical bacteria can be present in all seasons of the year, but their prevalence increases during hot weather. Mixed infections due to atypical bacteria may occur. The risk factors related to the development of RDS are prematurity, low weight, and orotracheal intubation.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11596979 | PMC |
http://dx.doi.org/10.3390/microorganisms12112328 | DOI Listing |
Medicine (Baltimore)
September 2025
Department of Infectious Diseases, Third People's Hospital of Chengdu, Chengdu, China.
Rationale: Japanese spotted fever (JSF) is a rare tick-borne disease caused by Rickettsia japonica. Atypical manifestations and a lack of standardized diagnostic assays often result in delayed diagnosis and treatment, potentially leading to life-threatening complications.
Patient Concerns: A 57-year-old immunocompetent female from a region with no previously reported JSF cases presented with acute-onset high-grade fever (39.
Medicine (Baltimore)
September 2025
Department of Spinal Surgery, The First Hospital of Jilin University, ChangChun, Jilin Province, China.
Rationale: Nocardia spp. are opportunistic pathogens that invade the human body via respiratory inhalation or direct skin wounds. Spinal nocardial osteomyelitis is a rare disease with only a few cases reported to date.
View Article and Find Full Text PDFIntern Emerg Med
September 2025
Dermatology Department, Hospital Universitario Puerta de Hierro Majadahonda, Calle Joaquín Rodrigo, 1, 28222, Majadahonda, Spain.
Mikrochim Acta
September 2025
Department of Surgical Oncology, Shaanxi Provincial People's Hospital, 256 Friendship West Road, Beilin District, Xi'an, 710068, Shaanxi, China.
Mycoplasma pneumonia, a primary aetiological agent of atypical pneumonia, necessitates the implementation of rapid point-of-care diagnostics. Lateral flow immunoassays (LFIAs) hold promise for point-of-care testing (POCT), yet their sensitivity levels are frequently constrained by probe affinity and matrix interference. We introduce an orientational labelling strategy that employs magnetic nanoparticles (MNPs) functionalized with staphylococcal protein A (SPA) to simultaneously enhance antibody orientation and facilitate magnetic enrichment.
View Article and Find Full Text PDFJ Infect Dev Ctries
August 2025
Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Background: Pneumonia with an empyema caused by anaerobic bacteria is rare but can be life-threatening, especially in immunocompromised patients.
Case Presentation: A 67-year-old man with diabetes and hypertension who presented with pneumonia and pleural effusion and was unresponsive to initial broad-spectrum antibiotics is presented. Next-generation sequencing identified Parvimonas micra and other pathogens.