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Introduction: Vapor-Tunnel™ (VT) consists of a very long pulse that uses the minimum peak power, causing the energy to pass through a previously created vapor channel or tunnel. There are studies that have shown acceptable ablation lithotripsy efficiency. Nevertheless, there are no in-vivo studies that have compared the VT performance according to the stone density.
Methods: A retrospective study of 152 patients who underwent RIRS using VT Ho:YAG laser was performed. We divided the patients according to the stone density (Group 1: < 1000UH vs. Group 2: > 1000UH). We assessed the lithotripsy efficiency (mm/JJ) and the laser-energy consumption (JJ/mm). The stone-free rate (SFR) was defined as the absence of stone fragments in a non-contrast abdominal computed tomography 4 weeks after the procedure.
Results: Ninety three patients were included in Group 1 and 59 in Group 2. Body mass index was higher in Group 1 and the median stone volume was higher in Group 2 (846 vs. 672 mm, p = 0.03). Total energy used (11.9 vs. 24 kj, p < 0.001), the laser emission time (19 vs. 30 min, p < 0.001), and the total operative time (60 vs. 85 min, p < 0.001) were lower in the Group 1. SFR was higher in Group 1 (96.7% vs. 57.6%, p < 0.001) with a global SFR of 81.6%. The ablation lithotripsy efficiency was higher in Group 1 (0.053 mm/JJ vs. 0.035 mm/JJ, p < 0.001).
Conclusions: VT Ho:YAG was associated with decreased laser time, operative time and laser-energy consumption in Group 1 than Group 2. Similarly, VT Ho:YAG increased lithotripsy efficiency and the SFR compared to hard stones with the same laser settings and pulse modality.
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http://dx.doi.org/10.1007/s11255-024-04289-x | DOI Listing |
Arch Esp Urol
August 2025
Department of Surgery, Hamdard Institute of Medical Sciences & Research, 110062 New Delhi, India.
Background: This study aimed to evaluate the correlation of Hounsfield unit (HU) to the success rate of medical expulsive therapy (MET) for distal ureteric calculus of size 4-10 mm.
Methods: All recruited patients were divided into two groups: Group A, who successfully passed the stone, and group B, who failed to expel the stone. All patients were prescribed with silodosin for a maximum period of 4 weeks.
Arch Osteoporos
September 2025
School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Unlabelled: The National Osteoporosis Guideline Group (NOGG) has updated the revised UK guideline for the assessment and management of osteoporosis and the prevention of fragility fractures in postmenopausal women, and men age 50 years and older. This guideline is relevant for all healthcare professionals involved in osteoporosis management.
Introduction: The UK National Osteoporosis Guideline Group (NOGG) first produced a guideline on the prevention and treatment of osteoporosis in 2008, with updates in 2013, 2017 and 2021.
JID Innov
November 2025
Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Patients with dermatomyositis (DM), an autoimmune disorder affecting the skin, muscle, and lung, have been reported to be at a heightened risk of clinical events, chiefly heart attacks and strokes, from atherosclerotic cardiovascular disease. In this study, we examined current cardiovascular management in a single-center study of all 388 patients who have DM with skin involvement, either with symptomatic muscle disease ("classic DM") or with clinically amyopathic DM. By the new guidelines, the most recent low-density lipoprotein cholesterol levels were above goal for 290 of 388 (74.
View Article and Find Full Text PDFJ Chem Phys
September 2025
Institute of Theoretical Physics, São Paulo State University (UNESP), Campus São Paulo, São Paulo, Brazil.
Hexagonal ice (Ih), the most common structure of ice, displays a variety of fascinating properties. Despite major efforts, a theoretical description of all its properties is still lacking. In particular, correctly accounting for its density and interatomic interactions is of utmost importance as a stepping stone for a deeper understanding of other properties.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
Department of Urology, The Second Hospital of Longyan, Longyan, Fujian Province, China.
Our study aimed to analyzed the effectiveness and safety of tubeless mini percutaneous nephrolithotomy (tmPCNL) and negative pressure combined with retrograde intrarenal surgery (nRIRS) for 2 to 3 cm renal stones. A total of 557 patients underwent tmPCNL or nRIRS for renal stones in our department from October 2022 to February 2024. Combining inclusion and exclusion criteria, 153 cases were included and divided into tmPCNL group (n = 76) and nRIRS group (n = 77) according to the surgical method.
View Article and Find Full Text PDF