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Objectives: This study aimed to analyze variations in the sella turcica (ST) concerning its size, shape, and bridging, providing first reference values in Austrian individuals. Additionally, it assessed associations between these morphological and demographic parameters and their correlation with patients' skeletal class.
Methods: 208 lateral cephalometric radiographs (154 female, 54 male; age 8-58 years) from DPU Dental Clinic (Austria) were included. Size, skeletal class, shape, age, and gender of ST were tested for significance in correlation using, (M)ANOVA, and chi-square.
Results: Linear dimensions of ST ranged from 11.1 to 12.9 mm across readers, with a standard deviation of 2.0-2.2 mm. Normal ST (49.76%) and round ST (58.77%) were the most frequent. ST bridging was detected in 6.97%. Skeletal class I appeared most frequently (54.8%). Statistical significance was observed between age, gender, and ST length, with further significant age effects on ST shape. Moreover, age showed significant modification of ST shape, while skeletal parameters appeared unaffected by other ST parameters.
Conclusions: These preliminary findings define normal ST dimensions in an Austrian population, offering reference values for clinical interpretation and broadening the available European data. Clear associations between morphological and demographic parameters were detected. Additionally, these findings may contribute to diagnostic and therapeutic strategies in orthodontics and craniofacial pathology. Future studies employing cone beam computed tomography (CBCT) along a larger sample size could enhance the generalizability of these findings.
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http://dx.doi.org/10.1007/s11282-024-00785-z | DOI Listing |
J Endocrinol Invest
September 2025
Department of Economics, Law, Cybersecurity, and Sports Sciences, University of Naples "Parthenope", Naples, Italy.
The sella turcica, a saddle-shaped depression of the sphenoid bone, serves as a critical anatomical structure housing the pituitary gland and holds significant evolutionary, clinical, and anthropological importance. This review traces the evolutionary origins of the sella turcica from early vertebrates through mammalian and primate evolution, emphasizing its role in the stabilization and protection of neuroendocrine functions. Morphological stability of the sella turcica across hominin evolution highlights strong selective pressures on cranial base anatomy, despite broader craniofacial diversification.
View Article and Find Full Text PDFWorld J Clin Pediatr
September 2025
Emergency Service, GHOL-Hopital de Nyon, Nyon 1260, Vaud, Switzerland.
Mucopolysaccharidoses (MPS) encompass a spectrum of inherited lysosomal storage disorders caused by deficiencies in enzymes required for glycosaminoglycan (GAG) degradation. These enzymatic deficits lead to GAG accumulation within lysosomes, resulting in progressive multiorgan damage, with skeletal abnormalities prominently affecting diagnostic imaging. Radiologists play a crucial role in identifying characteristic skeletal changes, including skull deformities like J-shaped sella turcica, cranial thickening, spinal abnormalities such as odontoid hypoplasia and kyphosis, and unique thoracic and pelvic malformations.
View Article and Find Full Text PDFMaedica (Bucur)
June 2025
Department of Internal Medicine, General Hospital "G. Hatzikosta" of Ioannina, Ioannina, Greece.
Cerebrospinal fluid (CSF) rhinorrhea is a relatively rare medical condition characterized by the drainage of CSF through the nasal cavity. Cerebrospinal fluid leakage can be attributed to a plethora of different causes, mostly traumatic or iatrogenic, but it can also be spontaneous. Due to its rare entity, CSF rhinorrhea is often a diagnostic trap and can be misdiagnosed and mistreated as rhinosinusitis or allergic rhinitis.
View Article and Find Full Text PDFOper Neurosurg
August 2025
Department of Neurosurgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Background And Objectives: Effective reconstruction of skull base defects after endonasal endoscopic surgery is essential to prevent complications such as cerebrospinal fluid leakage and infection. Traditional methods may not always provide optimal outcomes for certain defects. This study evaluates the feasibility of using the Amplatzer Septal Occluder (ASO) as an adjunctive tool for skull base reconstruction in a cadaveric model.
View Article and Find Full Text PDFCureus
July 2025
Department of Neurosurgery, Chrisitan Doppler Clinic Salzburg, Paracelsus Private Medical University, Salzburg, AUT.
This article presents the first documented case of a 61-year-old patient who underwent radical transnasal transsphenoidal endoscopic resection of a pituitary metastasis from a squamous cell carcinoma (SCC) of the tonsils. Only two other cases of pituitary metastases in SCC have been described in the literature to date. The patient was diagnosed with p16 and human papillomavirus (HPV)-positive tonsillar SCC in June 2022.
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