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http://dx.doi.org/10.1016/j.drugpo.2024.104655 | DOI Listing |
Kidney Med
July 2025
Department of Renal Medicine, St George Hospital, Kogarah, Australia.
Rationale & Objective: Chronic kidney disease-associated pruritus (CKDaP) is a distressing symptom affecting a significant proportion of people with advanced kidney disease. There are many studies of varying quality in the literature testing a wide variety of CKDaP therapies and no evidence-based consensus guidelines for management. We aimed to describe the breadth of treatments in use for CKDaP in real-world practice.
View Article and Find Full Text PDFSpine (Phila Pa 1976)
May 2025
Norton Leatherman Spine Center, Louisville, KY.
Study Design: Retrospective comparative cohort study.
Objectives: To examine the effects of chronic use of gabapentinoids (GPs) (alone or with opioids) on the outcomes of lumbar fusions.
Summary Of Background Data: Opioids have historically been the mainstay medications for pain management, but the ongoing opioid epidemic led physicians to look for alternatives.
Int J Drug Policy
December 2024
Department of Mental Health, Evangelisches Krankenhaus Castrop-Rauxel, Academic Teaching Hospital of the University of Duisburg-Essen, Castrop-Rauxel, Germany; Department of Psychiatry and Psychotherapy, Faculty of Medicine, Landschaftsverband Rheinland-Hospital Essen, University of Duisburg-Essen,
Front Pain Res (Lausanne)
October 2024
Department of Psychiatry, Saint Francis Hospital and Medical Center, Hartford, CT, United States.
Background: The escalating number of deaths related to opioid usage has intensified the pursuit of non-opioid alternatives for managing chronic pain. It's often observed that psychiatric comorbidities coexist in patients suffering from chronic pain. There are a variety of psychotropic medications that have demonstrated effectiveness in treating both psychiatric symptoms and pain.
View Article and Find Full Text PDFAnesthesiology
April 2024
University Hospital Würzburg, Würzburg, Germany.
Pain that accompanies deafferentation is one of the most mysterious and misunderstood medical conditions. Prevalence rates for the assorted conditions vary considerably but the most reliable estimates are greater than 50% for strokes involving the somatosensory system, brachial plexus avulsions, spinal cord injury, and limb amputation, with controversy surrounding the mechanistic contributions of deafferentation to ensuing neuropathic pain syndromes. Deafferentation pain has also been described for loss of other body parts (e.
View Article and Find Full Text PDF